“…The entity arises with bone pains and tenderness, renal failure, anemia, hypercalcemia, however, pulmonary involvement is rare, which is much more associated with bad prognosis, and encountered in the terminal period or plasma cell leukemi (2,3) Occasions such as chronic heart failure, pneumonia, tuberculosis (TB), connective tissue diseases, carcinoma, AIDS and other viral causes, and pulmonary embolism should be eliminated before the diagnosis of pulmonary or pleural involvement (4). Herein, a case is presented with a pulmonary parenchymal destruction due to acquired multiple myeloma who has a history of pulmonary TB.…”