Cytological diagnosis of a presacral myelolipoma: A case report diagnosed by fine‐needle aspiration

Hernández-Amate, Alicia; Ríos-Martín, Juan José; Díaz-Delgado, Mario; García-Escudero, Antonio; Otal-Salaverri, C; González‐Cámpora, Ricardo

doi:10.1002/dc.20802

Cited by 9 publications

(11 citation statements)

References 4 publications

(1 reference statement)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, a histopathological examination is necessary to obtain a correct diagnosis. Several studies have reported that CT- or US-guided fine needle biopsy examinations are useful for acquiring complementary diagnostic information [17–20]; however, there is a risk of tumor spread along the biopsy tract and sampling error. Clinician should be aware of the risks of malignant seeding, bleeding, and sampling errors during percutaneous or transrectal biopsy procedures [3, 4].…”

Section: Discussionmentioning

confidence: 99%

Incidental Presacral Myelolipoma Resembling the Liposarcoma: A Case Report and Literature Review

Tokuyama

Takeuchi

Kuroda

et al. 2016

Case Reports in Urology

View full text Add to dashboard Cite

Presacral myelolipomas are rare, benign, asymptomatic tumors composed of mature adipose tissue and hematopoietic elements, but fewer than 50 cases have been reported in the literature. They are usually discovered incidentally during imaging studies and are often misdiagnosed as liposarcoma, which have a malignant nature, because the imaging findings of myelolipoma can be similar to those of liposarcoma. It is challenging to distinguish presacral myelolipomas from other presacral fat-containing tumors without performing a histological examination. We should consider the possibility of a malignant tumor, and imaging-guided biopsy carries a risk of tumor spread along the biopsy tract. Therefore, surgical management might sometimes be required; however, it is not necessary in all cases. We present an incidentally detected case of presacral myelolipoma that was difficult to differentiate from other malignant tumors in a 71-year-old male.

show abstract

Section: Discussionmentioning

confidence: 99%

Incidental Presacral Myelolipoma Resembling the Liposarcoma: A Case Report and Literature Review

Tokuyama

Takeuchi

Kuroda

et al. 2016

Case Reports in Urology

View full text Add to dashboard Cite

show abstract

“…Their involvement is most frequently multifocal and predominantly affects the mediastinum; these lesions are usually poorly circumscribed and present minimal macroscopic fat. Moreover, an association with hepatosplenomegaly and chronic anemia is generally observed [3, 8, 13]. …”

Section: Discussionmentioning

confidence: 99%

“…The definitive diagnosis of presacral myelolipomas is still based on histology, given the potential overlapping imaging appearance with some of the more menacing fat-containing tumors described above [9, 13]. …”

Section: Discussionmentioning

confidence: 99%

An Unusual Fat-Containing Presacral Tumor in an Elderly Patient

Leite

Gonçalves

Ferreira

et al. 2014

Case Reports in Radiology

View full text Add to dashboard Cite

The authors present a case of a presacral myelolipoma diagnosed in an 84-year-old male patient with longstanding pelvic pain and past medical history of bladder cancer. Pelvic computed tomography (CT) revealed a well-encapsulated and lobulated presacral mass, with mixed fat and soft-tissue attenuation. Magnetic resonance (MR) imaging provided further confirmation of macroscopic intralesional fat and excluded either adjacent bone invasion or bladder cancer recurrence. A presacral myelolipoma was suspected based on imaging findings, with liposarcoma and teratoma having also been considered for the differential diagnosis. The histological confirmation of the tumor was only attained postoperatively. This case report alerts to the possible presacral location of myelolipomas, which should be considered for every fat-containing lesion detected in this region. The main clinical, imaging, and differential diagnoses of this entity are reviewed in this paper.

show abstract

“…This group includes myelolipomas, which typically arise in the adrenal, retroperitoneum, and presacral soft tissue. Myelolipomas show a characteristic mixture of mature adipose tissue and hematopoietic elements, although multilobated megakaryocytes may be mistaken for atypical stromal cells of ALT/WDLPS …”

Section: Lipomatous Tumorsmentioning

confidence: 99%

“…Myelolipomas show a characteristic mixture of mature adipose tissue and hematopoietic elements, although multilobated megakaryocytes may be mistaken for atypical stromal cells of ALT/WDLPS. 12,13…”

Section: Nonlipomatous Tumors With Adipocytic Componentmentioning

confidence: 99%

Application of ancillary studies in soft tissue cytology using a pattern‐based approach

Chebib

2018

Cancer Cytopathology

View full text Add to dashboard Cite

The cytologic diagnosis of soft tissue neoplasms has undergone many advances due to the development of numerous useful immunohistochemical markers and molecular assays that target specific molecular alterations. Ancillary tests, when used in conjunction with clinical, radiologic, and cytomorphologic features, allow for more accurate classification and refinement of differential diagnoses of soft tissue neoplasms. Soft tissue tumors encompass a diverse group of tumors showing a wide range of cytomorphologies that can be broadly grouped as lipomatous, myxoid, spindled, pleomorphic, round cell, and epithelioid. This pattern-based classification enables the formation of appropriate differentials; however, entities that share these basic morphologic patterns may vary greatly in their clinical behavior. The breadth of soft tissue tumors that can be diagnosed on cytologic preparations continues to increase with identification of defining molecular alterations that can be detected by conventional means (eg, fluorescence in situ hybridization) or by immunohistochemical surrogates. Furthermore, the emergence of high-throughput molecular techniques (eg, next generation sequencing) has potential roles for additional discovery and diagnostic applications. This review highlights the diagnostic role of ancillary tests in the context of a pattern-based approach to soft tissue cytology. Cancer Cytopathol 2018;000:000-000. © 2018 American Cancer Society.

show abstract

Cytological diagnosis of a presacral myelolipoma: A case report diagnosed by fine‐needle aspiration

Cited by 9 publications

References 4 publications

Incidental Presacral Myelolipoma Resembling the Liposarcoma: A Case Report and Literature Review

Incidental Presacral Myelolipoma Resembling the Liposarcoma: A Case Report and Literature Review

An Unusual Fat-Containing Presacral Tumor in an Elderly Patient

Application of ancillary studies in soft tissue cytology using a pattern‐based approach

Contact Info

Product

Resources

About