Cytological and bacteriological studies of intraoperative autologous blood in neurosurgery

Predicting the Risk of Perioperative Transfusion for Patients Undergoing Elective Hepatectomy

“…[12][13][14][15] Cell saver system is commonly used for some procedures (cardiovascular, orthopedic surgery), 16,17 but it is a controversial technique in oncology because of the uncertain risk associated with the reinfusion of malignant cells during resections. 18 The evaluation of the above mentioned factors suggests that a targeted strategy, which would use PADB or ANH only in those patients who are at high risk of requiring a perioperative transfusion, may reduce the inconveniences and the cost associated with the use of these alternative techniques. In a recently-completed clinical trial, 19 we showed that red blood cell transfusion rates decrease from 25% to 13% by the use of ANH, but the decrease was substantially more pronounced in patients losing at least 800 mL of blood during the operation (from 43% to 18%).…”

Removal of hemangiosarcoma cells from canine blood with a cell salvage system and leukocyte reduction filter

“…First, it has not been proven that viable tumor cells are shed during surgery for HSA. Tumor cells have been found in the operating field for several tumor types in humans . HSA cells have been found in free abdominal fluid in 3 dogs with hemoabdomen, but their viability is unknown .…”

Is cell salvage safe in liver resection? A pilot study

“…Bacterial contamination of intraoperatively cell salvaged and processed blood is a known phenomenon [21][22][23]. Even if the technique is applied to so-called "sterile" operations only, the contamination found varied considerably: Kudo and co-workers [24] described an overall bacterial contamination of 39% in autologous RBC during craniotomies. Bland and colleagues [25] detected bacterial contamination in 97% of samples taken from the CS after CPB and in orthopedic surgery, 28% of the autologous RBC was found to be contaminated [26].…”