Cytologic Findings of Breast Ductal Lavage and Concurrent Fine Needle Aspiration in Pleomorphic Lobular Carcinoma in Situ

Fine-needle-aspiration (FNA) Cytology for SRC Type Breast Cancer: 13 Case Reports

“…In addition to these features, our PLC case presented with SRCs. To our knowledge, there are only a few reports of the presence of SRCs in PLC; thus, the presence of SRCs in PLC remains under-recognized (29)(30). Our study indicates that PLC should be included in the differential diagnoses when SRCs are identified in FNA smears.…”

Pleomorphic lobular carcinoma of the breast: a comparison of cytopathological features with other lobular carcinoma variants

“…Another notable finding in our PLC cases is the presence of SRCs. To our knowledge, only a few reports previously demonstrated SRCs in PLC, leaving the presence of SRCs in PLC under‐recognized . In particular, no studies have compared the incidence of SRCs between PLC and non‐PLC cases based on FNA findings.…”

“…To our knowledge, only a few reports previously demonstrated SRCs in PLC, leaving the presence of SRCs in PLC underrecognized. 25,26 In particular, no studies have compared the incidence of SRCs between PLC and non-PLC cases based on FNA findings. In the present study, we did not see a significant difference in the incidence of SRCs, suggesting that the presence of SRCs is not a useful indicator to differentiate PLC from non-PLC using FNA samples.…”

Novel Tissue Types for the Development of Genomic Biomarkers

“…Although more invasive, ductal lavage yields more cells (Dooley et al, 2001;Li et al, 2005). These cells originate from the ductal epithelium and by studying them in the NAF, we can glean important information about the active biology within the ducts without the risks associated with biopsy (Dooley et al, 2001;King & Love, 2006;Miller et al, 2006). Much of this work has focused on the early identification of neoplasia using proteomic or cytological analysis of the cells isolated from this fluid (Dooley et al, 2001;Harigopal & Chhieng, 2010;King & Love, 2006;Mendrinos et al, 2005;Wrensch et al, 1992;Wrensch et al, 2001).…”