Cytologic Features of Solitary Fibrous Tumor of the Parotid Gland

Parotid Gland Solitary Fibrous Tumor: A Case Report and Clinicopathologic Review of 22 Cases from the Literature

“…Throughout the body, as well as in the head and neck region, SFT affects males and females with the same frequency [1,8,16,29]. Similarly, patients with parotid gland SFT were equally divided between male (n = 11) and female (n = 11) ( Table 2) [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. SFT usually affects middle aged adults, but it has also been found in young patients [1,8,18,29].…”

“…Patients with SFT of the parotid gland present with a well defined, palpable, slowly growing, painless mass which has often been present for a significant duration (range, 3-120 months; mean, 24.7 months) [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]28]. There was no significant difference in average duration of symptoms between males (mean, 32.6 months) and females (mean, 15.7 months) (P = 0.30) nor between left (mean, 29 months) or right sided tumors (mean, 16.2 months) (P = 0.46).…”

“…A review of the English literature based on a MEDLINE search from 1960 to 2011 was performed and all cases of solitary fibrous tumor involving the parotid specifically were included in the review, the majority of which were single case reports [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Clinical series of ''head and neck soft tissue tumors'' were selected if critical (Tables 1, 2).…”

Tumor fibroso solitario de la cavidad oral : Reporte de dos casos.

“…Son caracterizados por mostrar áreas hipercelulares e hipocelulares, una matriz colagenosa esclerótica y vasos sanguíneos en padrón hemangiopericítico. Aunque las células están distribuidas al azar, ellas pueden mostrar un padrón estoriforme (2,11,17). El tumor usualmente exhibe inmunoreactividad para vimentina, CD34, bcl-2, CD99 y factor XIIIa, pero es negativo para actina músculo específico, actina músculo liso, S100 y citoqueratinas (2,8,12,15,(17)(18)(19).…”

“…Fue primeramente descrito por Klemperer y Rabin en 1931, como una neoplasia de la pleura benigna o maligna. Posteriormente fue descrito en varios sitios extrapleurales como los pulmones, mediastino, peritoneo, médula espinal, tejidos blandos, tracto sinonasal, nasofaringe, tiroides, cavidad orbitaria, periostio, hígado, cápsula renal, piel, cavidad oral y glándulas salivales (2)(3)(4)(5)(6)(7)(8). En la literatura inglesa, encontramos relatados solamente 36 casos de TFS oral benigno (4,(8)(9)(10)(11)(12).…”