Cytologic examination of pancreatic juice, bile and duodenal juice in the diagnosis of pancreatic and biliary tract cancer.

Oikawa, Masamichi; Suzuki, Tamiko; Ishioka, Kuniharu; Miura, Yoko; Sato, Tai; Sato, Akira; Umetsu, Yoshiaki; Toyohara, Tokiaki; Hanzawa, Katsurou

doi:10.5795/jjscc.26.87

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“…This is because pancreatic secretions may cause cell degeneration, the number of cells that are present may be small and difficult to interpret, and cancer cells may be small and atypical in size and shape. The false-positive rate for benign pancreatic disease is reported to be 5.0% on endoscopic retrograde cholangiopancreatography (ERCP) ( 14 ), and the false positive rate for EUS-FNA cytology of solid pancreatic lesions was 1.1% (4/367) when only “positive” and 3.8% (14/367) when both “suspicious” and “positive” ( 15 ). Kobayashi et al reported that in false-positive cases of pancreatitis, when inflammation is severe and repetitive, degenerative processes (e.g.…”

Section: Discussionmentioning

confidence: 99%

Focal Type 2 Autoimmune Pancreatitis Mimicking Pancreatic Cancer: Treatment with Neoadjuvant Chemotherapy and Surgery

et al. 2023

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A 51-year-old man was referred to our hospital for the further examination of main pancreatic duct interruption. Imaging findings showed a 25-mm-diameter mass lesion located in the pancreatic head. Endoscopic ultrasonography (EUS)-guided fine-needle aspiration (FNA) was performed on the mass. Cytology suggested adenocarcinoma, but the histological diagnosis was not confirmed. We made a comprehensive diagnosis of resectable pancreatic cancer. The mass shrank after preoperative adjuvant chemotherapy, and the patient underwent surgery. The final pathological diagnosis was type 2 autoimmune pancreatitis (AIP). Two years after surgery, AIP had not recurred in the remaining pancreas.

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Section: Discussionmentioning

confidence: 99%