Cytokine Antibody Arrays: A Useful Tool in Biotechnology for the Screening of Specific Biomarkers in Eyes Diseases

Abstract

Some of the eye diseases may require invasive methods like surgical biopsy, or less invasive but with a limited diagnostic accuracy like fine needle aspiration biopsy. Tears could be a non-invasive method to obtain samples to analyzing eye diseases. Antibody arrays, mini array of protein, is a recently established proteomic biotechnology providing unique opportunities for various applications, such as protein expression profiling, biomarker discovery, disease diagnostics, prognostics and more. The use of mini arrays of protein to analyze the presence of inflammation proteins in tears may represent a non-invasive technique which can be used to identify potential biomarkers of eye diseases. It can open a new perspective to discover new molecules, so as to use them as possible targets for the development of innovative pharmacological approaches.