Cytoarchitecture, myeloarchitecture, and parcellation of the chimpanzee inferior parietal lobe

Reyes, Laura D.; Kim, Jae Won; Issa, Habon; Hopkins, William D.; Mackey, Scott; Sherwood, Chet C.

doi:10.1007/s00429-022-02514-w

Cited by 5 publications

(4 citation statements)

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“…Anatomical connections confirmed the boundaries previously detected by cytoarchitecture and identified several subdivisions not previously reported in brain mapping of human and other non-human primates 36,57 . For example, the IPL contained 5 subregions in our atlas (Figure S10A, Figure S24) and showed consistent rostral-caudal topological pattern across various parcellation schemes, except for a ventral subregion located in the parietal operculum, which has been reported both by anatomical connection-based and cytoarchitectonic parcellation 32,58,59 . For another example, the chimpanzee’s IFG has received extensive attention because of its potential association with the evolution of communication and language 60,61 .…”

Section: Discussionsupporting

confidence: 68%

“…The terminology of the parcellation is provided in Table S2. Although detailed whole-brain cytoarchitectonic data from chimpanzee brains are unavailable for alignment, we utilized the cytoarchitectonic maps of three well-described regions for validation 21,40,[46][47][48][49] and found good consistency between histology and connectivity-base parcellation (inferior parietal lobule, Figure S4A; inferior frontal gyrus, Figure S4B; superior temporal gyrus, Figure S4C). The details of the parcellation results for each initial region are shown in Figure S5-S30.…”

Section: Connectivity-based Parcellation Of the Chimpanzee Brainmentioning

confidence: 99%

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Comparative Analysis of Human-Chimpanzee Divergence in Brain Connectivity and its Genetic Correlates

Wang,

Cheng,

et al. 2024

Preprint

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Chimpanzees (Pan troglodytes) are humans’ closest living evolutionary relatives, making them the most directly relevant comparison point for understanding human brain evolution. By zeroing in on the differences in brain connectivity between humans and chimpanzees, it can provide key insights into the specific evolutionary changes that occurred along the human lineage. However, conducting fair comparisons of brain connectivity between humans and chimpanzees remains challenging, as cross-species brain atlases established within the same framework are currently lacking. Without the availability of cross-species brain atlases, the region-wise connectivity patterns between humans and chimpanzees cannot be directly compared. To address this gap, we built the first Chimpanzee Brainnetome Atlas (ChimpBNA) by following the well-established connectivity-based parcellation framework. Leveraging this new resource, we found substantial divergence in connectivity patterns across most association cortices, notably in the lateral temporal and dorsolateral prefrontal cortex between the two species. Intriguingly, these patterns significantly deviate from the expected cortical expansion during brain evolution. Additionally, we identified regions displaying connectional asymmetries between species, likely resulting from evolutionary divergence. Genes associated with these divergent connectivities were found to be enriched in cell types crucial for cortical projection circuits and synapse formation. These genes exhibited more pronounced differences in expression patterns in regions with higher connectivity divergence, suggesting a potential foundation for brain connectivity evolution. Therefore, our study not only provides a fine-scale brain atlas of chimpanzees but also highlights the connectivity divergence between humans and chimpanzees in a more rigorous and comparative manner and suggests potential genetic underpinnings for the observed divergence in brain connectivity patterns between the two species. This can help us better understand the origins and development of uniquely human cognitive capabilities.

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Section: Discussionsupporting

confidence: 68%

Section: Connectivity-based Parcellation Of the Chimpanzee Brainmentioning

confidence: 99%

Comparative Analysis of Human-Chimpanzee Divergence in Brain Connectivity and its Genetic Correlates

Wang,

Cheng,

et al. 2024

Preprint

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“…SMI-32 immunostaining performed byGregoriou et al (2006) characterized macaque area Opt as having a lower density of large pyramidal neurons in layer IIIc as compared to area PG. This description is similar to the one we offer here for capuchin area Opt Reyes et al (2022). recently studied the cytoarchitecture, myeloarchitecture, and parcellation of the chimpanzee inferior parietal lobe.…”

mentioning

confidence: 67%

“…Reyes et al. (2022) recently studied the cytoarchitecture, myeloarchitecture, and parcellation of the chimpanzee inferior parietal lobe. They identified four major areas on the lateral convexity of the chimpanzee IPL (PF, PFG, PG, OPT), in addition to two opercular areas (PFOP, PGOP), similar to what has been described for the macaque.…”

Section: Discussionmentioning

confidence: 99%

Architecture of the inferior parietal cortex in capuchin monkey

Bonfim

Mayer

Nascimento-Silva

et al. 2023

J of Comparative Neurology

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We studied the organization of the inferior parietal cortex (IPC) in five capuchin monkey (6 hemispheres) using cytoarchitectonic (Nissl), myeloarchitectonic (Gallyas), and immune‐architectonic (SMI‐32 monoclonal antibody) techniques. We partitioned the IPC into five distinct areas: PFG, PG, Opt, PFop, and PGop. Since we used parasagittal sections, we were not able to study area PF due to its far lateral position, which yielded slices that were tangential to the pial surface. Areas PFG, PG, and Opt were in the convexity close to the lateral sulcus, while PFop and PGop were positioned more posteriorly, in the opercular region of IPC. Of all the five regions, area Opt was the one most similar to its analogue in the macaque, especially as revealed with SMI‐32 staining. Namely, in both primate species area Opt showed a low density of large pyramidal neurons. Additionally, the apical dendrites of these neurons were sparse and vertically orientated, resembling columns. We also found area PG to be similar: both species exhibited cell body layers with a radial arrangement. On the other hand, Nissl staining revealed area PFG to be architectonically different between New and Old‐World monkeys: PFG in the capuchin showed a comparatively higher cell density than in macaques, especially in layers II and IV. These results suggest that evolution may have enabled the functional specialization of these brain regions based on behavioral demands of upper limb use. The small differences in the IPC of the two primates may be linked to interspecies variability.

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The angular gyrus: a special issue on its complex anatomy and function

Rockland

Graves

2022

Brain Struct Funct

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Cytoarchitecture, myeloarchitecture, and parcellation of the chimpanzee inferior parietal lobe

Cited by 5 publications

References 61 publications

Comparative Analysis of Human-Chimpanzee Divergence in Brain Connectivity and its Genetic Correlates

Comparative Analysis of Human-Chimpanzee Divergence in Brain Connectivity and its Genetic Correlates

Architecture of the inferior parietal cortex in capuchin monkey

The angular gyrus: a special issue on its complex anatomy and function

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