Cyto-colpo-histological Study in Sexual Workers

Abstract

Objective. To determine the false‐negative, false‐positive, sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) rates of Pap smears and colposcopy in sexual workers. Materials and Methods. Four hundred thirty‐eight prostitutes were given a gynecological examination, Pap smear, and colposcopic examination of the cervix. A cervical biopsy was taken under colposcopic guidance when there was abnormal epithelium. Results. There were 81 premalignant and malignant lesions. Twenty‐two Pap smear reports were abnormal: 17 CIN1, four CIN2, and one CIN3. Pap smears had a 14.4% false‐negative rate, 0.9% false‐positive rate, sensitivity 22.2%, specificity 98.8%, NPV 84.4%, and PPV 81.8%. Eighty‐four biopsies were taken from abnormal colposcopic findings, and 96.4% were reported as premalignant and malignant lesions. Colposcopy had a 0.8% false‐positive rate, sensitivity 100%, specificity 99.2%, NPV 100%, and PPV 96.4%. Conclusions. Pap smear had a low‐sensitivity and colposcopy had a high sensitivity and specificity.