Cystite incrustante à Corynebacterium urealyticum

Alterations in the Genital Microbiota in Women With Spinal Cord Injury

“…17 In women with spinal cord injury classified as American Spine Injury Association A, who have no genital sensation and are totally dependent on wheelchairs, physical alterations in the vulvovaginal area resulting from their sedentary life may increase the likelihood of Corynebacterium species prolifereration. 18,19 In support of increased Corynebacterium species growth under an altered vaginal milieu, the continuous use of pads and diapers by women in our study was associated with isolation of Corynebacterium species (P,.023). There are no prior studies related to preferential Corynebacterium species proliferation in women with spinal cord injury.…”

“…18,19 In the present study, a lower frequency of Lactobacillus species and increased Corynebacterium species in the population with spinal cord injury and urinary loss could be associated with an increased prevalence of some other microorganism that was not isolated by the culture medium used for this study. There are no studies in the literature that related urinary loss with the presence of microorganisms such as Corynebacterium species and a lower frequency of Lactobacillus species in vaginal culture in women with spinal cord injury.…”

Microbiological and clinical features of Corynebacterium urealyticum: urinary tract stones and genomics as the Rosetta Stone

“…Most cases of encrusted cystitis have required surgical resection of the bladder encrustations, as well as prolonged (more than 1 month) antimicrobial treatment. Antibiotics successfully used in this condition have been glycopeptides [7,8,69,76–79,83,85,89], tetracyclines [5,7,8,58,83], and fluoroquinolones [7,8,58,77,80,90]. Teicoplanin has been successfully used in two patients with encrusted cystitis caused by C. urealyticum , even without cystoscopic resection of the stones, which were spontaneously eliminated [79].…”

“…It is thus not surprising that some patients with this condition become suicidal. Encrusted cystitis causes long‐lasting symptoms in the lower urinary tract, with frequent relapses [1,2,5,7,8,30,46,58,69,75–90]. Immunosuppression is usually less frequent than in patients with acute infections, but most patients have experienced previous bladder diseases and have undergone urological manipulations.…”

“…Two‐dimensional echography of the bladder can show hyperechogenic foci, and the uroscanner can show calcified plaques in the bladder. It is also possible to demonstrate, in some cases, ureterohydronephrosis [88,90] by echography or intravenous pyelography. Encrusted cystitis is usually confirmed by cystoscopy, which, at the same time, allows the surgical resection of the encrusted lesions.…”