Cystic Lesions of the Pancreas

Khan, Atif; Khosa, Faisal; Eisenberg, Ronald L.

doi:10.2214/ajr.10.4378

Cited by 33 publications

(24 citation statements)

References 9 publications

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“…2 The pancreatic cystic lesions may also be categorized into unilocular cysts (pseudocysts, intraductal papillary mucinous neoplasms), multilocular macrocysts ( mucinous cystic neoplasms), microcysts (serous cystadenomas), cysts with solid component (ductal adenocarcinomas with cystic degeneration, solid pseudopapillary tumour). 3 Mesenchymal lesions (lymphangiomas, hemangiomas) and metastatic tumours also come under the differentials of cystic lesions of pancreas. In the neoplastic category, cystic tumours of pancreas are less common than solid one's accounting for less than 1% cases, but this may vary in different centres and some studies show upto 15% of cystic pancreatic tumours.…”

Section: Discussionmentioning

confidence: 99%

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Morphologic features in cystic lesions of pancreas-a retrospective analysis

Cicy

Gopinathan

et al. 2018

Int J Adv Med

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Background: Cystic lesions of pancreas consist of a broad spectrum of reactive, benign and malignant conditions. The most common among cystic pancreatic lesions is pseudocyst of pancreas. Cystic tumours of pancreas are less common than solid one’s accounting for less than 1% according to some studies. Literature review showed only a few extensive studies on cystic lesions of pancreas, especially from South India.Methods: Our research is a descriptive histopathological analysis of 38 cases of cystic lesions of pancreas, done in the department of pathology of our institution, over a period of 5 years.Results: We received a total of 38 cases of cystic lesions of pancreas. The age distribution ranged from 17 to 77 years. Male to female ratio was 24: 14. There were neoplastic and non neoplastic entities. Pseudocyst of pancreas was the most common cystic lesion (12 cases). Benign neoplasms included serous cystadenomas, mucinous cystadenomas and lymphangiomas. Ductal adenocarcinomas with cystic degeneration and adenocarcinomas with mucinous component were some of the malignant cystic lesions.Conclusions: Cystic pancreatic lesions accounted for 24% of all the pancreatic lesions received in our institution during the period of this study. 24 cases (63%) were benign lesions and 14 cases (37 %) were malignant. Though cystic lesions of pancreas especially neoplasms are less frequent than solid neoplasms, it is important to study their diagnostic features since the management differs. Imaging studies may be similar in some cystic lesions. A proper clinicoradiological correlation and detailed investigational work up will aid in the correct diagnosis.

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Section: Discussionmentioning

confidence: 99%

“…They can be unilocular or multilocular and may affect both sexes. 3 Pseudocysts are localized fluid collections representing sequestered pancreatic secretions. In our study, there were 12 pseudo cysts accounting for 31.6% of the total cystic lesions and 50% of benign cysts of pancreas.…”

Section: Pseudocystsmentioning

confidence: 99%

Morphologic features in cystic lesions of pancreas-a retrospective analysis

Cicy

Gopinathan

et al. 2018

Int J Adv Med

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“…Cyst wall, septa and mural nodules are more pronounced after contrast administration ( Fig. 12 C) (6,7,8). The MCN content is generally mucinous (with fluid densities at CT, hyperintense at T2 and hypointense at T1) (9, 7), but it can also be aqueous, necrotic or hemorrhagic (2).…”

Section: Mucinous Cystic Neoplasms (Mcn)mentioning

confidence: 95%

“…11 D), but can sometimes cause duct obstruction by compression, leading to distal pancreatitis (7,11,8).…”

Section: Mucinous Cystic Neoplasms (Mcn)mentioning

confidence: 99%

Pancreatic Cystic Neoplasms: Diagnosis, Management and Indications for Surgical Procedures. Part II

Bauer¹

2018

chr

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“…In these cases, clear depiction of numerous discrete small fluid-filled cysts at MRI (due to the high sensitivity of the method in detecting fluid) will usually facilitate correct diagnostic (Fig. 8 B) (28,29). Uncommonly, an SCN may have an oligolocular or macrocystic appearance and/or no central scar, which makes them difficult to differentiate from other mucinous forms of cystic neoplasms.…”

Section: Morphologymentioning

confidence: 99%

Pancreatic Cystic Lesions: Diagnostic, Management and Indications for Operation. Part I

Bauer¹

2017

chr

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Chirurgia, 112 (2), 2017 97 RezumatÎn ultimele trei decenii am observat o creştere a frecvenţei depistării şi evaluării leziunilor chistice pancreatice (PCL). Acestea prezintă o paletă variată de trăsături imagistice şi clinice. Diagnosticul şi diferenţierea leziunilor chistice pancreatice este deosebit de importantă, din cauza riscului concret de malignizare. Principalul motiv al acestei lucrari este conştientizarea existenţei acestor leziuni şi folosirea extinsă a modalităţilor imagistice cu secţiuni transversale, tehnică aflată într-o continuă dezvoltare (1). De obicei, PCL sunt diagnosticate din întâmplare în timpul investigării unor dureri abdominale independente şi nespecifice folosind proceduri imagistice obişnuite, CT sau IRM. Leziunile chistice pancreatice reprezintă o colecţie eterogenă histologică, care poate avea un spectru larg de diagnostice de la complet benign la potenţial malign, la carcinom in situ şi până la invaziv (2,3). În 1978, Compagno şi Oertel au fost primii care au observat distincţia crucială între neoplaziile chistice seroase şi mucinoase ale pancreasului şi au explicat importanţa identificării neoplaziilor mucinoase din cauza potenţialului lor malign latent sau evident (4,5). De atunci, interesul pentru PCL a crescut semnificativ, mai ales după ce a fost identificată importanţa şi prevalenţa neoplaziilor papilare mucinoase intraductale (IPMN). În prezent, PCL reprezintă o provocare frecventă şi dificilă în practica clinică, datorită creşterii detectării acestora la pacienţi asimptomatici şi a lipsei de înţelegere a aspectelor care ţin de comportamentul biologic al acestor neoplazii. Diferenţele importante în ceea ce priveşte rezultatul lor final şi identificarea acestora tot mai frecventă au plasat neoplaziile în atenţia chirurgilor, anatomopatologilor, gastroenterologilor, Abbreviations:

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Cystic Lesions of the Pancreas

Cited by 33 publications

References 9 publications

Morphologic features in cystic lesions of pancreas-a retrospective analysis

Morphologic features in cystic lesions of pancreas-a retrospective analysis

Pancreatic Cystic Neoplasms: Diagnosis, Management and Indications for Surgical Procedures. Part II

Pancreatic Cystic Lesions: Diagnostic, Management and Indications for Operation. Part I

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