Cystic fibrosis management in pediatric population—from clinical features to personalized therapy
Alice Nicoleta Azoicai,
Ancuta Lupu,
Laura Mihaela Trandafir
et al.
Abstract:Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). In 1949, it's been identified as a monogenic disease and was thought to primarily affect individuals of Northern European descent. It was the most prevalent autosomal recessive disease that shortens life. With the availability of multiple testing methodologies nowadays, there is a chance to create novel and enhanced treatment options. Even in the absenc… Show more
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