Cystic adventitial degeneration of the popliteal artery: Lectin histochemical study

Marzo, Luca di; Rocca, Carlo Della; d’Amati, Giulia; Gallo, Piero; Sciacca, Vincenzo; Mingoli, Andrea; Cavallaro, Antonino

doi:10.1016/s0950-821x(05)80113-6

Cited by 22 publications

(19 citation statements)

References 11 publications

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“…Certain biochemical similarities have been found e.g. a rich content of hyaluronic acid and a positive alcian blue stain response of the cystic content 38 . However, the biochemical composition is otherwise significantly different, and studies of the chemical analyses of the fluid contents and the histochemistry of the cyst lining have therefore not provided compelling evidence in support of this theory 43,46 .…”

Section: Etiology Of Cadmentioning

confidence: 89%

“…At the biochemical level, the absence of Ulex europeus 1 reactivity of the endothelium-like cells of the lining of adventitial cysts suggests a non-vascular origin because these histochemical markers are present in the vascularly derived endothelium 38 . The ganglionic theory itself is supported by the findings of Patel and Cormier 39 , who described a tendinous ganglion on the posterior surface of the knee in addition to popliteal artery CAD but not the communication between these lesions.…”

Section: Etiology Of Cadmentioning

confidence: 99%

“…Also the higher hyaluronic acid concentration in the adventitial cyst fluid compared to that in the synovial fluid suggests developmental aberration rather than the concept according to which the cysts are formed and maintained by communication with a synovial space 49 . On the other hand, the histochemical markers for synovium are absent in adventiti al cysts 38,44 . The microtraum atic theory was postulated on the basis of cases of popliteal artery CAD in young adults employed in heavy physical labour 50 , and in patients engaged in extreme sports and vigorous exercise [25][26][27][28] .…”

Section: Etiology Of Cadmentioning

confidence: 99%

“…Similarly, the finding of an extended affected condition of the branches of the vessel, specifically of the genicular branches being affected by cysts in the case of popliteal CAD (ref. 28,38 ) is considered a possible predictor of a higher risk of recurrence. However, the reports do not provide a recommendation regarding the resection of these branches.…”

Section: Treatment Of Cadmentioning

confidence: 99%

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Cystic Adventitial Disease of the Popliteal Artery: Report on Three Cases and Review of the Literature

Drác¹,

Köcher²,

Utíkal³

et al. 2011

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Section: Etiology Of Cadmentioning

confidence: 89%

Section: Etiology Of Cadmentioning

confidence: 99%

Section: Etiology Of Cadmentioning

confidence: 99%

Section: Treatment Of Cadmentioning

confidence: 99%

See 2 more Smart Citations

Cystic Adventitial Disease of the Popliteal Artery: Report on Three Cases and Review of the Literature

Drác¹,

Köcher²,

Utíkal³

et al. 2011

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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“…Su etiología sigue siendo incierta [11][12][13][14][15] , existiendo cuatro hipótesis: -Traumatismos repetidos, frecuentemente mínimos, que producirían una degeneración de la adventicia de la arteria generando así los cambios quísticos en la pared de esta. -Degeneración mucosa de la adventicia ligada a un trastorno generalizado del organismo.…”

Section: Discussionunclassified

Degeneración quística de la arteria poplítea: Presentación de caso clínico

et al. 2015

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Evidence to support that adventitial cysts, analogous to intraneural ganglion cysts, are also joint‐connected

et al. 2012

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Cystic adventitial disease (CAD) is a rare condition in which cyst is found within a vessel, typically producing symptoms of vascular compromise. Most commonly located in the popliteal artery near the knee, it has been reported in arteries and veins throughout the body. Its pathogenesis has been poorly understood and various surgical approaches have been recommended. We extrapolated some recent information about a similar condition, intraneural ganglion cyst affecting the deep fibular (peroneal) nerve, to the prototype, CAD of the popliteal artery. In intraneural ganglion cysts affecting the deep fibular nerve we have shown that an articular (neural) branch is the conduit between the superior tibiofibular joint and the main parent nerve for which epineurial dissection of joint fluid can occur. We hypothesized that the same principles would apply to CAD and that an articular (vascular) branch would be the conduit from the knee joint leading to dissection to the main parent vessel. We reviewed five patients with CAD of the popliteal artery in whom MRIs were available: two treated by the primary author well familiar with the proposed articular theory, and three treated by others at our institution, less familiar with it. We then reviewed the literature critically to assess for additional evidence to support our articular (synovial) theory and an anatomic explanation. In the two cases treated by the primary author a joint connection was identified on high resolution MRI prospectively and intraoperatively through the middle genicular artery (MGA); postoperatively in these cases there was no recurrence. In the other three cases, a joint connection was not identified on imaging or at operation. Reinterpretation of these cases revealed a joint connection through the MGA in the one patient who had preoperative imaging and subclinical persistence/recurrence in the two patients who underwent postoperative MRIs done for other reasons. Our review of the literature and imaging studies revealed unrecognized joint connections in CAD to the knee and other joints as well as evidence that the MGA is the conduit in cases of CAD of the popliteal artery. We believe that adventitial cysts originate in neighboring joints and dissect within articular (vascular) branches. In our opinion, the unifying articular theory and the principles introduced for intraneural ganglion cysts apply equally to common and rare sites of adventitial cysts.

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Cystic adventitial degeneration of the popliteal artery: Lectin histochemical study

Cited by 22 publications

References 11 publications

Cystic Adventitial Disease of the Popliteal Artery: Report on Three Cases and Review of the Literature

Cystic Adventitial Disease of the Popliteal Artery: Report on Three Cases and Review of the Literature

Degeneración quística de la arteria poplítea: Presentación de caso clínico

Evidence to support that adventitial cysts, analogous to intraneural ganglion cysts, are also joint‐connected

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