Cysteine-assisted overgrowth of gold nanorods to prepare highly branched gold nanoantennas with tunable morphological and plasmonic properties

Bi, Cuixia; Wang, Zhixiu; Zhao, Hongyan; Liu, Guangqiang

doi:10.1039/d3ce00685a

Cited by 1 publication

(1 citation statement)

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“…A wide range of gold nanomaterials with varying sizes and shapes, such as gold nanospheres, gold nanorods (AuNRs), gold nanoshells, gold nanocages, gold nanoclusters (AuNCs), and nanostars, have been fabricated [ 78 ]. Different morphologies dictate distinct properties, and AuNPs with anisotropic shapes (e.g., AuNRs and gold nanostars) or hollow structures (e.g., gold nanoshells and gold nanocages) can exhibit LSPR peaks in the near-infrared (NIR) region [ 79 ]. AuNRs are rod-like gold nanomaterials that are commonly utilized in light-induced photothermal (photodynamic) therapy [ 80 ], gold nanocages, characterized by hollow interiors and porous walls, are considered more preferable drug delivery vehicles [ 81 ]; gold nanostars possess three distinct surface curvatures, making them exceptionally valuable for biological sensing, imaging, and localized chemical manipulations [ 82 ], gold nanoclusters, are ultra small in size (typically less than 3 nm in diameter) and possess unique fluorescent properties.…”

Section: Preparation Of Polysaccharide Gold Nanoparticlesmentioning

confidence: 99%

Research Progress of Polysaccharide-Gold Nanocomplexes in Drug Delivery

Song,

Aipire,

Dilxat

et al. 2024

Pharmaceutics

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Clinical drug administration aims to deliver drugs efficiently and safely to target tissues, organs, and cells, with the objective of enabling their therapeutic effects. Currently, the main approach to enhance a drug’s effectiveness is ensuring its efficient delivery to the intended site. Due to the fact that there are still various drawbacks of traditional drug delivery methods, such as high toxicity and side effects, insufficient drug specificity, poor targeting, and poor pharmacokinetic performance, nanocarriers have emerged as a promising alternative. Nanocarriers possess significant advantages in drug delivery due to their size tunability and surface modifiability. Moreover, nano-drug delivery systems have demonstrated strong potential in terms of prolonging drug circulation time, improving bioavailability, increasing drug retention at the tumor site, decreasing drug resistance, as well as reducing the undesirable side effects of anticancer drugs. Numerous studies have focused on utilizing polysaccharides as nanodelivery carriers, developing delivery systems based on polysaccharides, or exploiting polysaccharides as tumor-targeting ligands to enhance the precision of nanoparticle delivery. These types of investigations have become commonplace in the academic literature. This review aims to elucidate the preparation methods and principles of polysaccharide gold nanocarriers. It also provides an overview of the factors that affect the loading of polysaccharide gold nanocarriers with different kinds of drugs. Additionally, it outlines the strategies employed by polysaccharide gold nanocarriers to improve the delivery efficiency of various drugs. The objective is to provide a reference for further development of research on polysaccharide gold nanodelivery systems.

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