Cystadenocarcinoma of the intrahepatic bile duct in a dog

Abstract

A 14-year-old spayed female Shih-Tzu was referred to the Veterinary Medical Teaching Hospital of Konkuk University for evaluation of an abdominal mass. In diagnostic imaging, two large cystic masses were identified. The affected liver lobes were surgically resected, and the specimens were submitted for histopathological evaluation and immunohistochemical staining. The two cystic lesions were diagnosed as biliary cystadenocarcinoma (BCAC). Recurrence and regional invasion were identified on ultrasonography 36 days postoperatively. The patient died on postoperative day 271. To the best of our knowledge, previously reported case studies of BCAC in dogs presented limited clinical information. In this report, we present a detailed picture comprising a range of clinical information and histopathological examination of BCAC in a dog.

Computed tomographic appearance of canine hepatic alveolar echinococcosis

“…Notably, there is usually an absence of visible capsule, mineralization, or septation, providing clear distinctions from hepatic AE lesions. In contrast, hepatic cystadenomas and cystadenocarcinomas may exhibit septation, but the septae typically appear thin and well‐defined, sometimes with nodular thickening 23,24 . Both types of tumors display contrast enhancement within the capsule and septae 23–25 .…”

“…In contrast, hepatic cystadenomas and cystadenocarcinomas may exhibit septation, but the septae typically appear thin and well‐defined, sometimes with nodular thickening 23,24 . Both types of tumors display contrast enhancement within the capsule and septae 23–25 . Furthermore, they often feature additional characteristics such as papillary excrescences and mural nodules 23,25 …”

“…23,24 Both types of tumors display contrast enhancement within the capsule and septae. [23][24][25] Furthermore, they often feature additional characteristics such as papillary excrescences and mural nodules. 23,25 Splenic and nonparenchymal hemangiosarcomas manifest as heterogeneous, particularly cavernous, vaguely delineated mass lesions with varying degrees of contrast accumulation.…”