Abstract:Various species of freshwater fish regulate the expression of certain
proteins in response to environmental contamination. Previous research
has shown that CYP1A expression increases in response to contaminant
levels, and can result in increased tumor formation. Fish in
contaminated environments would thus benefit by downregulating the
expression of CYP1A to reduce tumor prevalence as an adaptive strategy.
Alternatively, regulation of the CYP1A protein in fish can serve as a
bioindicator of the pollution level… Show more
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