Cydonia oblonga M., A Medicinal Plant Rich in Phytonutrients for Pharmaceuticals

Abstract

Cydonia oblonga M. is a medicinal plant of family Rosaceae which is used to prevent or treat several ailments such as cancer, diabetes, hepatitis, ulcer, respiratory, and urinary infections, etc. Cydonia oblonga commonly known as Quince is rich in useful secondary metabolites such as phenolics, steroids, flavonoids, terpenoids, tannins, sugars, organic acids, and glycosides. A wide range of pharmacological activities like antioxidant, antibacterial, antifungal, anti-inflammatory, hepatoprotective, cardiovascular, antidepressant, antidiarrheal, hypolipidemic, diuretic, and hypoglycemic have been ascribed to various parts of C. oblonga. The polysaccharide mucilage, glucuronoxylan extruded from seeds of C. oblonga is used in dermal patches to heal wounds. This review focuses on detailed investigations of high-valued phytochemicals as well as pharmacological and phytomedicinal attributes of the plant.

A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

“…Various parts of plants such as roots, flowers, and leaves are used to treat a number of ailments in traditional systems of medicines (Unani‐Tibb, Ayurveda, and Chinese) owing to the presence of bioactives (Anwar et al, ; Ashraf, Muhammad, Hussain, & Bukhari, ; Muhammad, Hussain, Anwar, Ashraf, & Gilani, ; Muhammad, Hussain, Jantan, & Bukhari, ). According to the World Health Organization (WHO, ), phytomedicines are trusted by more than 80% of people around the globe.…”

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“…Since one of the factors contributing to menorrhagia is the high concentration of prostaglandins, especially prostaglandin F2α21, the presence of flavonoids in "Quince" leads to the reduction of menorrhagia 14 . One of the causes of abnormal uterine bleeding is inflammatory reactions in the endometrium.…”

“…Moreover, "Quince" has a healing effect on skin ulcers, decrease of nausea, decrease of saliva secretion, lowers blood glucose and has an antioxidant effect 14 . Regarding the high prevalence of menorrhagia, the severity of its complications and its role in quality of life of women, the importance of early treatment with low complications, the use of" Quince paste" in traditional medicine clinics and lack of clinical studies in this regard, this research was conducted to examine the effect of "Quince paste" on uterine bleeding in patients with menorrhagia.…”

“…"Quince" compositions contain tannins, polysaccharides, glycosides, carotenoids, pectin, coumarin, flavonoids, malic acid, Vitamins B and C and pro Vitamin A 11,12 . In Iranian Traditional Medicine (ITM) resources, "Quince" is used for the treatment of cough, catarrh, bronchitis, asthma, diarrhea, abdominal pains, dysentery, hemorrhoids, uterine bleeding and uterine discharge 13,14 .…”

Guava flavonoid glycosides prevent influenza A virus infection via rescue of P53 activity

“…Through this mechanism, the virus is able to largely adapt to the body's immune system, which may not be able to recognize and confer immunity to new influenza strains . Plant flavonoids are a free type of polyphenolic compounds, like glycosides, which are commonly formed in flowers, fruits, vegetables, and beverages (wine and tea) . It is increasingly imperative to use the plant flavonoid glycosides as antimicrobial agents including antibiotic‐resistant gram‐positive and gram‐negative bacteria .…”