Cycloruthenated Compounds – Synthesis and Applications

Abstract

The syntheses of cycloruthenated compounds by several methods, and especially by the C-H activation pathway, have been reviewed. Many ruthenium-containing starting materials lead to these interesting organometallic compounds, which have found various applications in different fields of chemistry. Their reactivity highlights both the variety of reactions that were found to occur at the Ru-C bonds as well as the inertness of the organometallic moiety when these species are exposed to strongly oxidizing molecules or to reactive halogenation reagents. Their use as catalyst precursors showed them to be particularly efficient for hydrogenation reactions, either by H 2 or by hydride transfer.

Ruthenium(III) Cyclometalates Obtained by Site‐Specific Orthometallation and Their Reactivity with Nitric Oxide: Photoinduced Release and Estimation of NO Liberated from the Ruthenium Nitrosyl Complexes

“…Complexes 3s and 4s were similar to 2a in terms of NO generation in solution. Ruthenium cyclometalates have never been used for photoinduced delivery of nitric oxide [30] and complexes described in this report demand their application in photodynamic therapy.…”

Cyclometalation Using d-Block Transition Metals: Fundamental Aspects and Recent Trends

“…67,270,271 Moreover, ruthenacycles are amongst the most active catalysts known to date for transfer hydrogenation reactions. 272,273 An excellent review has recently appeared, 28 which compiles a vast range of precursors and ligand settings used for cycloruthenation. Perhaps the two most important conclusions from this overview are that, first, cycloruthenation is extremely versatile and of very broad scope.…”

Platinum(II) and palladium(II) complexes with (N,N′) and (C,N,N′)− ligands derived from pyrazole as anticancer and antimalarial agents: Synthesis, characterization and in vitro activities

“…Cyclometallated complexes derived from N-donor ligands have attracted great interest during the last decade due to their properties and applications in a wide variety of fields [10,[20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] and compounds of this kind containing Pd(II), Pt(II), Ru(II), Ir(III) Rh(III) and Au have shown promising cytotoxic activities [10,20,[27][28][29][30][31][32][33][34][35][36]. Few cyclopalladated complexes derived from pyrazole are known [37][38][39][40][41] and, to the best of our knowledge, their cytotoxicity has only been reported once [41].…”