Cyclophosphamide versus cytarabine mobilization of hematopoietic stem cells with G-CSF stimulation in myeloma patients subjected to autologous stem cell transplantation
Abstract:The aim of our study was to compare different regimes of hematopoietic stem cell (HSC) mobilization, i.e., cyclophosphamide combined with granulocyte colony-stimulating factor (Cy/G-CSF), versus cytarabine with G-CSF (Ara-C/G-CSF). Efficiency and toxicity of these treatment regimens were assessed. Achievement of partial remission of the disease was sufficient for successful mobilization. CD34+ cell numbers in the blood showed a significant correlation with total number of CD34+ yielded by apheresis on the same… Show more
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