Cycloid Psychoses and Schizoaffective Psychoses – A Comparison of Different Diagnostic Classification Systems and Criteria

Zaudig, Michael

doi:10.1159/000284666

Cited by 14 publications

(3 citation statements)

References 15 publications

(18 reference statements)

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“…The current findings are complementary to, rather than replicative of, Strik's earlier studies since cycloid psychosis is not clinically synonymous with current definitions of schizoaffective disorder (Vogl and Zaudig, 1985; Zaudig, 1990; Peralta et al, 2007). Nonetheless, both sets of findings underscore the fact that, despite the commonly held view that P300 amplitude reduction is a relatively non-specific electrophysiological abnormality observed in a number of psychiatric disorders, it may nonetheless be useful in demarcating or validating diagnostic boundaries within the clinical heterogeneity encompassed by chronic psychotic disorders.…”

Section: Discussionsupporting

confidence: 75%

Neurophysiological distinction between schizophrenia and schizoaffective disorder

Mathalon

2009

Front. Hum. Neurosci.

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Schizoaffective disorder (SA) is distinguished from schizophrenia (SZ) based on the presence of prominent mood symptoms over the illness course. Despite this clinical distinction, SA and SZ patients are often combined in research studies, in part because data supporting a distinct pathophysiological boundary between the disorders are lacking. Indeed, few studies have addressed whether neurobiological abnormalities associated with SZ, such as the widely replicated reduction and delay of the P300 event-related potential (ERP), are also present in SA. Scalp EEG was acquired from patients with DSM-IV SA (n = 15) or SZ (n = 22), as well as healthy controls (HC; n = 22) to assess the P300 elicited by infrequent target (15%) and task-irrelevant distractor (15%) stimuli in separate auditory and visual ”oddball” tasks. P300 amplitude was reduced and delayed in SZ, relative to HC, consistent with prior studies. These SZ abnormalities did not interact with stimulus type (target vs. task-irrelevant distractor) or modality (auditory vs. visual). Across sensory modality and stimulus type, SA patients exhibited normal P300 amplitudes (significantly larger than SZ patients and indistinguishable from HC). However, P300 latency and reaction time were both equivalently delayed in SZ and SA patients, relative to HC. P300 differences between SA and SZ patients could not be accounted for by variation in symptom severity, socio-economic status, education, or illness duration. Although both groups show similar deficits in processing speed, SA patients do not exhibit the P300 amplitude deficits evident in SZ, consistent with an underlying pathophysiological boundary between these disorders.

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Section: Discussionsupporting

confidence: 75%

Neurophysiological distinction between schizophrenia and schizoaffective disorder

Mathalon

2009

Front. Hum. Neurosci.

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“…52 • Cycloid psychosis on its classic forms: hyperkinetic-akinetic motility psychosis; excited-inhibited confusion psychosis; and anxiety-happiness psychosis. [53][54][55][56][57] • Other atypical psychoses 58,59 outside Kraepelinian dicothomy.…”

Section: The Bipolar Disorders Spectrummentioning

confidence: 99%

Schizophrenia–schizoaffective–bipolar spectra: an epistemological perspective

Marques

Ouakinin

2019

CNS Spectr.

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For decades clinicians and researchers have been thinking and writing about the spectrum of schizophrenia disorders. Indeed both Kraepelin and Bleuler believed in schizophrenia as a spectrum, both in a clinical (individual) and hereditary (family) continuum, from just some exquisite personality traits to unquestionable chronic and debilitating psychosis. Other authors would put the schizophrenia spectrum disorders on different levels of continuum: developmental, psychofunctional, existential, and genetic. Here, we would like to present an historical chronology for the schizophrenia–schizoaffective–bipolar spectra plus a tridimensional model for these spectra: the first axis for categories (affective versus nonaffective psychoses), the second axis for dimensions (personality versus full blown psychosis), and a third axis for biomarkers (remission versus relapse). We believe that without the schizophrenia–schizoaffective–bipolar spectra concept in our minds all our efforts will keep failing one the hardest quest: searching for biomarkers in schizophrenia and related disorders.

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“…Here is a nucleus of features providing an acceptable basis for prognosis and therapy [4][5][6], The validation of the concept by means of external criteria -social adaptation, physiological cor relates -has recently been accomplished in several studies [7][8][9], There also seems to be a consensus on questions pertaining to the rela tionships of Leonhard's concept to overlap ping or synonymous concepts -e.g. the bouf fées délirantes described by Magnan and the atypical psychosis described by Mitsuda [3,[10][11][12][13][14],…”

mentioning

confidence: 99%

Cycloid Psychosis and Affective Disorder: Borderland Cases

Jönsson¹

1992

Psychopathology

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A subsample of untreated cycloid psychoses satisfying the requirements for major affective disorder according to DSM-III was compared with a subsample of cycloid psychoses getting other DSM-III diagnoses. The concept of cycloid psychosis applied thus was wider than permitted by the criteria stipulated by Perris and Brockington with respect to the prominence of the mood component. Since it could be demonstrated that no decisive differences prevailed with respect to frequencies of single features tested, a modified discriminant analytic procedure was applied. In this analysis, 76% of cases were correctly assigned. On average affective cases were more similar to the score profile derived from the nonaffective group than nonaffective cases were to the same profile, i.e. to themselves. Symptomatologically the affective cases had their main point in a distinctive confusion syndrome.

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Cycloid Psychoses and Schizoaffective Psychoses – A Comparison of Different Diagnostic Classification Systems and Criteria

Cited by 14 publications

References 15 publications

Neurophysiological distinction between schizophrenia and schizoaffective disorder

Neurophysiological distinction between schizophrenia and schizoaffective disorder

Schizophrenia–schizoaffective–bipolar spectra: an epistemological perspective

Cycloid Psychosis and Affective Disorder: Borderland Cases

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