Cyclodextrins as Bricks for Tuning Polymer Properties

Abstract

Cyclodextrins are natural cyclic oligosaccharides with a cone shape delimiting a hydrophobic cavity. The rims of cyclodextrins can be functionalized in order to improve their properties. Based on this, cyclodextrins can be linked to polymer chains, which further allows the tuning of the polymer properties. This review describes the methods of polymer functionalization with cyclodextrins and highlights the changes in the physicochemical properties of these materials. This chapter is focused on polymers in solution and in gel states. Cyclodextrin-based polymers are evaluated by various physicochemical methods, such as rheology, calorimetry, and spectroscopy (electron paramagnetic resonance, fluorescence, nuclear magnetic resonance (NMR), Fourier transform infrared (FT-IR), etc.). Both natural and synthetic polymers are considered in this chapter.

Physicochemical Changes of Alginate and Polyacrylate Mixture Induced by Interactions of the Appended Units

“…The most common host unit attached to a polymer is represented by cyclodextrins (CDs). Functional polymers based on cyclodextrin have been DOI: 10.1002/macp.202200444 designed and studied reported in time highlighting the enhancement of encapsulation and release ability, the improvement of mechanical characteristics, biodegradability, [1][2][3] Alg is an anionic polysaccharide that is generally used in biomedical and pharmaceutical applications due to its biodegradability, nontoxicity, biocompatibility, low immunogenicity, etc. [4][5][6][7] A number of studies reported on the synthesis of Alg modified with cyclodextrin units.…”