Cyclodextrin-assisted assembly of stimuli-responsive polymers in aqueous media

Abstract

This review explores the advances in stimuli-responsive polymeric inclusion complexes, comprising of cyclodextrins, in aqueous media. Cyclodextrin complexation allows these polymeric systems to possess tailored physical properties that permit them to form novel supramolecular structures. By including and combining stimuli-responsive characteristics, these special systems can transform into various morphologies when exposed to different kinds of external stimuli. A wide variety of these stimuliresponsive polyrotaxanes and functionalized cyclodextrin polymers that possess interesting supramolecular characteristics are discussed, with specific focus on pH-, temperature-, photo-and redox-sensitive systems. These unusual polymer/cyclodextrin systems provide a basis for many useful applications, such as drug delivery, environmentally friendly coatings, personal home care products, separation processes, food processing, and microelectronics.

Thermal inverse phase transition of azobenzene hydroxypropylcellulose in aqueous solutions

“…The hydroxyl groups are exposed in the exterior, making CD hydrophilic and water soluble. The interior of the toroid is less hydrophilic than the aqueous environment and thus able to host other hydrophobic molecules to form inclusion compounds (Yuen and Tam 2010) (Fig. 11a).…”

Preparation and sorption studies of polyester microsphere copolymers containing β-Cyclodextrin

“…These types of copolymer materials were shown to display tunable physicochemical properties that extended beyond the range of conventional cross linked sorbent materials. Tunable physicochemical properties of such copolymers include their morphology, structure (e.g., inclusion and interstitial domains) and hydrophile-lipophile balance (HLB) [8,14]. Thus, rational sorbent design of CD-based copolymers should account for the inclusion site accessibility, the role of the interstitial framework domains, cross link density, and the relative HLB of the sorbent framework [15].…”

Soft aggregates formed by a nonionic phytosterol ethoxylate and β-cyclodextrin in aqueous solution

“…As reported previously, both the sterol group and the PEO chain could be included by ␤-CD [34][35][36]. To determine the nature of the interaction between BPS-30 and ␤-CD, the 2D 1 H-1 H NMR (NOESY) spectra were measured and the obtained results are shown in Fig.…”