Cyclic strain of poly (methyl methacrylate) surfaces triggered the pathogenicity of Candida albicans

The Effects of Angelica ternata Extract from Kyrgyzstan on the Formation of Candida albicans ATCC 10231 Biofilms

“…Of note, Candida infections are commonly associated with biofilms that can form either on mucosal surfaces or on plastic surfaces of indwelling devices as well [5]. The matrix mannan-glucan complex in biofilm is conserved across the Candida genus, including Candida albicans, C. tropicalis, and C. glabrata [6,7]. Biofilms formed by a variety of Candida spp.…”

“…Biofilms have the potential to modulate host immunity throughout various developmental stages [13,14]. During mature biofilm formation, the ECM contributes to resistance to host defenses, and with the dispersal of fungal cells, a more virulent phenotype might appear to aggravate the pathogenesis [1,6,15]. The wide prevalence of Candida albicans, the ability to quickly adapt to changing environmental conditions and resistance to antifungal drugs and disinfectants, including due to good communication and cooperation with other microorganisms and the interweaving of biofilms, allow us to consider such YLF as a dangerous infectious agent capable of causing many diseases both in human and veterinary medicine [16][17][18][19].…”