Cyclic negative pressure wound therapy: an alternative mode to intermittent system

Lee, Kangwoo N; Ben-Nakhi, Muneera; Park, Eun Jeong; Hong, Joon Pio

doi:10.1111/iwj.12201

Cited by 25 publications

(16 citation statements)

References 25 publications

(26 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We chose the cyclic mode as it oscillates between −50 and −125 mm Hg to increase the mechanical stretch and minimize the pressure on the wound. 13 , 29 – 31 Among many mechanisms behind the positive effect of NPWT over incision, we first looked at the change in perfusion of the skin after application. The wounds treated with NPWT showed greater perfusion.…”

Section: Discussionmentioning

confidence: 99%

Negative Pressure Wound Therapy on Closed Surgical Wounds With Dead Space

Suh

Lee

Park

et al. 2016

Annals of Plastic Surgery

View full text Add to dashboard Cite

BackgroundClosed incisional wound surgery frequently leaves dead space under the repaired skin, which results in delayed healing. The purpose of this study was to evaluate the effect of negative pressure wound therapy (NPWT) on incisional wounds with dead space after primary closure by evaluating the fluid volume through the suction drain, blood flow of the skin, tensile strength, and histology of the wounds.MethodsBilateral 25-cm-long incisional wounds with dead space were created on the back of 6 pigs by partially removing the back muscle and then suturing the skin with nylon sutures. NPWT (experimental group) or gauze dressing (control group) was applied over the closed incision for 7 days. Analysis of the wound included monitoring the amount of closed suction drain, blood perfusion unit, tensile strength of the repaired skin, and histology of the incision site.ResultsThe drainage amount was significantly reduced in the experimental group (49.8 mL) compared to the control group (86.2 mL) (P = 0.046). Skin perfusion was increased in the experimental group with statistical significance compared to the control group (P = 0.0175). Collagen staining was increased in the experimental group. The tensile strength of the incision site was significantly higher in the experimental group (24.6 N at 7 days, 61.67 N at 21 days) compared to the control group (18.26 N at 7 days, 50.05 N at 21 days) (P = 0.02).ConclusionThis study explains some of the mechanism for using NPWT in closed incision wounds with dead space. It demonstrates that NPWT significantly reduces drainage amount, increases skin perfusion, increases tensile strength, and has the tendency to promote collagen synthesis for closed wound with dead space indicating enhanced healing.

show abstract

Section: Discussionmentioning

confidence: 99%

Negative Pressure Wound Therapy on Closed Surgical Wounds With Dead Space

Suh

Lee

Park

et al. 2016

Annals of Plastic Surgery

View full text Add to dashboard Cite

show abstract

“…By using cyclic mode which oscillates between −40 and −75 mm Hg, the patient feels less pain because of the fact that the pressure never drops to zero as the intermittent mode. 9 Moderated amount of serous discharge was removed from the wound. With this approach, there was no further bleeding related to NPWT on this patient with high risk for bleeding.…”

Section: Discussionmentioning

confidence: 99%

Using a Contradictory Approach to Treat a Wound Induced by Hematoma in a Patient With Antiphospholipid Antibody Syndrome Using Negative Pressure Wound Therapy

Jang

Hong

Bordianu

et al. 2015

The International Journal of Lower Extremity Wounds

View full text Add to dashboard Cite

A 48-year-old woman with antiphospholipid syndrome (APS) had multiple skin necrosis caused by massive bleeding and hematoma collection at the right lower leg, left thigh, and abdomen. During the first month, we did surgical debridement every 2 to 3 days with meticulous coagulation and applied negative pressure wound therapy (NPWT). Then as the base showed initial granulation, we changed the NPWT every 4 days. NPWT was used with lower pressure and cyclic mode (-40 to -75 mm Hg) to minimize trauma and to reduce the possibility of bleeding from the wounds. After 2 months of NPWT treatment, all the wounds eventually healed with secondary intension despite the patient's condition with diabetes, hemodialysis, anticoagulant use, and corticosteroid therapy. This report supports the idea that if accompanied by conservative debridement with meticulous bleeding control, application of NPWT in low pressures and close monitoring of the patient, NPWT is possible to use even in wounds of patients with risk for bleeding.

show abstract

“…Recent advancement in technology introduced that a hydrosurgery system can debride while preserving viable tissues and can irrigate simultaneously allowing reduced surgical time . Another good tool is using negative‐pressure wound therapy that will enhance the rate of granulation formation .…”

Section: Surgical Approachmentioning

confidence: 99%

Innovations in diabetic foot reconstruction using supermicrosurgery

Suh

Hong

2016

Diabetes Metabolism Res

View full text Add to dashboard Cite

The treatment of diabetic foot ulceration is complex with multiple factors involved, and it may often lead to limb amputation. Hence, a multidisciplinary approach is warranted to cover the spectrum of treatment for diabetic foot, but in complex wounds, surgical treatment is inevitable. Surgery may involve the decision to preserve the limb by reconstruction or to amputate it. Reconstruction involves preserving the limb with secure coverage. Local flaps usually are able to provide sufficient coverage for small or moderate sized wound, but for larger wounds, soft tissue coverage involves flaps that are distantly located from the wound. Reconstruction of distant flap usually involves microsurgery, and now, further innovative methods such as supermicrosurgery have further given complex wounds a better chance to be reconstructed and limbs salvaged. This article reviews the microsurgery involved in reconstruction and introduces the new method of supermicrosurgery.

show abstract

Cyclic negative pressure wound therapy: an alternative mode to intermittent system

Cited by 25 publications

References 25 publications

Negative Pressure Wound Therapy on Closed Surgical Wounds With Dead Space

Negative Pressure Wound Therapy on Closed Surgical Wounds With Dead Space

Using a Contradictory Approach to Treat a Wound Induced by Hematoma in a Patient With Antiphospholipid Antibody Syndrome Using Negative Pressure Wound Therapy

Innovations in diabetic foot reconstruction using supermicrosurgery

Contact Info

Product

Resources

About