1993
DOI: 10.1016/s0040-4039(00)77463-6
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Cyclic derivatives of 3,3-diphenylalanine (Dip) (II), novel α-amino acids for peptides of biological interest

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Cited by 21 publications
(7 citation statements)
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“…5 H -Dibenzo[ a , d ]cycloheptene-5-acetic Acid (5d). Compound 5d was synthesized via the method described in ref . Tacky yellow solid, yield = 70%.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…5 H -Dibenzo[ a , d ]cycloheptene-5-acetic Acid (5d). Compound 5d was synthesized via the method described in ref . Tacky yellow solid, yield = 70%.…”
Section: Methodsmentioning
confidence: 99%
“…The requisite 3,3-disubstituted propionic acids were obtained commercially ( 5a ), synthesized via literature methods ( 5b , 5c , 5d , 5f ), or synthesized via routes developed in our laboratories (Table ). The saturated bridged tricyclic 5e was synthesized by reduction of the corresponding unsaturated compound 5d .…”
Section: Chemistrymentioning
confidence: 99%
“…Reaction of the chiral potassium enolate of 31 with trisyl azide gave, after hydrolysis of the chiral auxiliary, product 32. 41,42 This reaction sequence was used for the synthesis of many unusual amino acids including diphthamide, 43 phosphotyrosine, 44 -methylphenylalanine, 45 and ethynyltyrosine. 46 In 1998, Ahn and co-workers showed that this azidation reaction could be performed on chiral sultam auxiliaries.…”
Section: Electrophilic Azidation Using Evans' Chiral Auxiliarymentioning
confidence: 99%
“…After removal of the chiral auxiliary with LiOH/H202, the azido acid was hydrogenated over Pd/C (Fig. 19) (Evans et al, 1989(Evans et al, , 1990aChen et al, 1992;Beylin et al, 1993;Lundquist and Dix, 1998).…”
Section: Electrophilic Arninationmentioning
confidence: 99%