In mid-2019, the Air Force Research Laboratory (AFRL) asked RAND Project AIR FORCE (PAF) for assistance understanding how cyber-related risks compare with other risks to its defense-industrial supply chains-a scope that included supply chains for hardware, not supply chains for software per se-and exploring implications for risk assessment and mitigation and for research. Over the next 18 months, PAF sought to characterize cyber-related risks to supply chains and identify directions for addressing the distinct-unique, exceptional, and sometimesreinforcing-challenges that cyber-related risks pose to defense-industrial supply chains and, hence, to supply chain risk management (SCRM).This report discusses that PAF research effort. The effort was part of a larger undertaking that also explored national security policies at the nexus of cybersecurity and SCRM, as well as tools and frameworks for addressing cyber-related risks. The report complements a body of recent RAND work, including several studies on the cybersecurity of Department of the Air Force weapon systems and industrial control systems, cyber vulnerabilities, and global supply chain risks. It should be of interest to those seeking to secure the supply of defense industrial products from the risks of cyberattacks, primarily from the perspective of SCRM, and across research and policy communities.