Cyanoethylation of Aromatic Aldehyde Imines Containing a Hydroxy Group in the β‐ or γ‐Position. Synthesis of 3‐Cyanoethyl‐1,3‐oxazacycloalkanes.

Abstract

Ring closure reactions O 0130 Cyanoethylation of Aromatic Aldehyde Imines Containing a Hydroxy Group in the βor γ-Position. Synthesis of 3-Cyanoethyl-1,3-oxazacycloalkanes. -(KON'KOVA, S. G.; ABOVYAN, G. M.; KHACHATRYAN, A. K.; BADASYAN, A. E.; PANOSYAN, G. A.; SARGSYAN, M. S.; Russ.

Cyanoethylation of Aromatic Aldehyde Imines Containing a Hydroxy Group in the β- or γ-Position. Synthesis of 3-Cyanoethyl-1,3-oxazacycloalkanes

“…We previously reported [1] on the formation of 2-aryl-3-cyanoethyltetrahydro-1,3-oxazines and 2-aryl-3-cyanoethyl-1,3-oxazolidines in reactions of acrylonitrile with Schiff bases I derived from aromatic aldehydes and containing a hydroxy group in the βor γ-position of the alkyl chain on the nitrogen atom. In continuation of these studies, in the present work we examined in more detail the reaction of compounds I with acrylonitrile in order to elucidate general relations holding therein and reveal tautomerism of the initial hydroxy-containing Schiff bases.…”