Abstract:Cyanocobalamin (the compound name of Vitamin B12) is the only mineral vitamin that is essential for growth and development and cannot be produced by animals. Some studies have found that...
“…The process of MuSC proliferation is not solely regulated by endogenous functional genes, but also influenced by various extracellular factors, including the extracellular matrix, hormones, growth factors and vitamins. 9,10 Vitamin C (VC) is a polyhydroxy compound with a molecular formula of C 6 H 8 O 6 . It exists in two important biological forms: the reduced form of ascorbic acid (AA) and the oxidized form of dehydroascorbic acid (DHA).…”
This study shows that VC binds to Pax7 to up-regulate the expression and nuclear translocation of Pax7, thereby up-regulating the expression of Myf5 to promote proliferation of C2C12 myoblasts and mice skeletal muscle post-injury regeneration.
“…The process of MuSC proliferation is not solely regulated by endogenous functional genes, but also influenced by various extracellular factors, including the extracellular matrix, hormones, growth factors and vitamins. 9,10 Vitamin C (VC) is a polyhydroxy compound with a molecular formula of C 6 H 8 O 6 . It exists in two important biological forms: the reduced form of ascorbic acid (AA) and the oxidized form of dehydroascorbic acid (DHA).…”
This study shows that VC binds to Pax7 to up-regulate the expression and nuclear translocation of Pax7, thereby up-regulating the expression of Myf5 to promote proliferation of C2C12 myoblasts and mice skeletal muscle post-injury regeneration.
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