Cyanobacteria Microcystis aeruginosa Contributes to the Severity of Fish Diseases: A Study on Spring Viraemia of Carp

Palíková, Miroslava; Kopp, Radovan; Kohoutek, Jiří; Bláha, Luděk; Mareš, Jan; Ondráčková, Petra; Papežíková, Ivana; Minářová, Hana; Pojezdal, Ľubomír; Adamovský, Ondřej

doi:10.3390/toxins13090601

Cited by 4 publications

(2 citation statements)

References 52 publications

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“…In a sub-chronic study, Palikova et al [150] found that a single cyanobacterial biomass, or the presence of white spot disease (Ichthyophthirius multifiliis), created a stimulating effect on the immune response, while the combined group caused immunosuppression in common carp. Polikova et al [151] demonstrated that a cyanobacterial biomass enhanced the severity of the immune dysfunction of common carp injected with Carp sprivivirus, which indicated that the co-exposure to cyanobacteria and virus worsened the fish immunity. Such evidence proved that the synergistic effects of MCs and microbial pathogens should not be neglected.…”

Section: Microbial Pathogens In Aquatic Ecosystemsmentioning

confidence: 99%

Microcystin-Induced Immunotoxicity in Fishes: A Scoping Review

Wang

Hung

Kurobe

et al. 2021

Toxins

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Cyanobacteria (blue-green algae) have been present on Earth for over 2 billion years, and can produce a variety of bioactive molecules, such as cyanotoxins. Microcystins (MCs), the most frequently detected cyanotoxins, pose a threat to the aquatic environment and to human health. The classic toxic mechanism of MCs is the inhibition of the protein phosphatases 1 and 2A (PP1 and PP2A). Immunity is known as one of the most important physiological functions in the neuroendocrine-immune network to prevent infections and maintain internal homoeostasis in fish. The present review aimed to summarize existing papers, elaborate on the MC-induced immunotoxicity in fish, and put forward some suggestions for future research. The immunomodulatory effects of MCs in fish depend on the exposure concentrations, doses, time, and routes of exposure. Previous field and laboratory studies provided strong evidence of the associations between MC-induced immunotoxicity and fish death. In our review, we summarized that the immunotoxicity of MCs is primarily characterized by the inhibition of PP1 and PP2A, oxidative stress, immune cell damage, and inflammation, as well as apoptosis. The advances in fish immunoreaction upon encountering MCs will benefit the monitoring and prediction of fish health, helping to achieve an ecotoxicological goal and to ensure the sustainability of species. Future studies concerning MC-induced immunotoxicity should focus on adaptive immunity, the hormesis phenomenon and the synergistic effects of aquatic microbial pathogens.

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Section: Microbial Pathogens In Aquatic Ecosystemsmentioning

confidence: 99%

Microcystin-Induced Immunotoxicity in Fishes: A Scoping Review

Wang

Hung

Kurobe

et al. 2021

Toxins

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show abstract

“…The presence of these toxins can hinder the multiple uses of water as it can cause socioeconomic, environmental, and public health impacts, in addition to altering the organoleptic properties of the treated water supply [ 8 , 9 , 10 , 11 ]. It is noteworthy that the consumption of aquatic organisms may also be a risk factor because they may bioaccumulate cyanotoxins in their tissues [ 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Identification of Cyanobacteria and Its Potential Toxins in the Joanes I Reservoir, Bahia, Brazil

Menescal

Almeida

Sales

et al. 2023

Toxins

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The Joanes I Reservoir is responsible for 40% of the drinking water supply of the Metropolitan Region of Salvador, Bahia, Brazil. For water sources such as this, there is concern regarding the proliferation of potentially toxin-producing cyanobacteria, which can cause environmental and public health impacts. To evaluate the presence of cyanobacteria and their cyanotoxins in the water of this reservoir, the cyanobacteria were identified by microscopy; the presence of the genes of the cyanotoxin-producing cyanobacteria was detected by molecular methods (polymerase chain reaction (PCR)/sequencing); and the presence of toxins was determined by liquid chromatography with tandem mass spectrometry (LC-MS/MS). The water samples were collected at four sampling points in the Joanes I Reservoir in a monitoring campaign conducted during the occurrence of phytoplankton blooms, and the water quality parameters were also analysed. Ten cyanobacteria species/genera were identified at the monitoring sites, including five potentially cyanotoxin-producing species, such as Cylindrospermopsis raciborskii, Cylindrospermopsis cf. acuminato-crispa, Aphanocapsa sp., Phormidium sp., and Pseudanabaena sp. A positive result for the presence of the cylindrospermopsin toxin was confirmed at two sampling points by LC-MS/MS, which indicated that the populations are actively producing toxins. The analysis of the PCR products using the HEPF/HEPR primer pair for the detection of the microcystin biosynthesis gene mcyE was positive for the analysed samples. The results of this study point to the worrisome condition of this reservoir, from which water is collected for public supply, and indicate the importance of the joint use of different methods for the analysis of cyanobacteria and their toxins in reservoir monitoring.

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Metagenomics analysis of bacterial communities in the periphytic biofilms from floating fish cages and their relationship with water physicochemical parameters

et al. 2024

Preprint

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In this study, we report the presence of bacterial community in terms of abundance and taxonomic biodiversity from periphytic biofilm samples attached to the surface of floating fish cage components in the Pahang River and their relationship with water physicochemical parameters. Periphytic biofilm samples were collected from five sites located in the different districts alongside the Pahang River. Water physicochemical parameters assessment was also conducted simultaneously during the sampling process. Bacterial deoxyribonucleic acid (DNA) was then extracted from periphytic biofilm samples and sequenced on NovaSEQ6000 by Illumina Next Generation Sequencing (NGS) to construct metagenomics libraries. The results indicated the predominant phyla were Cyanobacteria, which accounted for more than half of the total bacteria detected, followed by Proteobacteria, Planctomycetota and Actinobacteriota. At the class level, the top five most detected classes were Cyanobacteria, Alphaproteobacteria, Gammaproteobacteria, Actinomycetia and Planctomycetes. Statistical analysis discovered a significant correlation between the bacterial abundance and distribution with the water physicochemical parameters. This study is the first report of bacterial abundance and its relationship with water physicochemical parameters in the Pahang River through metagenomic analysis.

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Cyanobacteria Microcystis aeruginosa Contributes to the Severity of Fish Diseases: A Study on Spring Viraemia of Carp

Cited by 4 publications

References 52 publications

Microcystin-Induced Immunotoxicity in Fishes: A Scoping Review

Microcystin-Induced Immunotoxicity in Fishes: A Scoping Review

Identification of Cyanobacteria and Its Potential Toxins in the Joanes I Reservoir, Bahia, Brazil

Metagenomics analysis of bacterial communities in the periphytic biofilms from floating fish cages and their relationship with water physicochemical parameters

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