Cyanobacteria

Puschner, Birgit; Moore, Caroline E.

doi:10.1016/b978-1-4557-0717-1.00043-0

Cited by 5 publications

(4 citation statements)

References 42 publications

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“…Some research found that some species in Cyanobacteria could produce toxic metabolites known as cyanotoxins [ 55 ]. Moreover, the toxicity of cyanotoxins is strain-specific [ 56 ]. Therefore, positive identification does not predict the hazard level, that is to say, it is difficult to speculate the consequences of the increase of Cyanobacteria caused by FB1, and more studies are needed.…”

Section: Discussionmentioning

confidence: 99%

Response of Fecal Bacterial Flora to the Exposure of Fumonisin B1 in BALB/c Mice

Zhang

Chen

Jiang

et al. 2021

Toxins

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Fumonisins are a kind of mycotoxin that has harmful influence on the health of humans and animals. Although some research studies associated with fumonisins have been reported, the regulatory limits of fumonisins are imperfect, and the effects of fumonisins on fecal bacterial flora of mice have not been suggested. In this study, in order to investigate the effects of fumonisin B1 (FB1) on fecal bacterial flora, BALB/c mice were randomly divided into seven groups, which were fed intragastrically with 0 mg/kg, 0.018 mg/kg, 0.054 mg/kg, 0.162 mg/kg, 0.486 mg/kg, 1.458 mg/kg and 4.374 mg/kg of FB1 solutions, once a day for 8 weeks. Subsequently, feces were collected for analysis of microflora. The V3-V4 16S rRNA of fecal bacterial flora was sequenced using the Illumina MiSeq platform. The results revealed that fecal bacterial flora of mice treated with FB1 presented high diversity. Additionally, the composition of fecal bacterial flora of FB1 exposure groups showed marked differences from that of the control group, especially for the genus types including Alloprevotella, Prevotellaceae_NK3B31_group, Rikenellaceae_RC9_gut_group, Parabacteroides and phylum types including Cyanobacteria. In conclusion, our data indicate that FB1 alters the diversity and composition of fecal microbiota in mice. Moreover, the minimum dose of FB1 exposure also causes changes in fecal microbiota to some extent. This study is the first to focus on the dose-related effect of FB1 exposure on fecal microbiota in rodent animals and gives references to the regulatory doses of fumonisins for better protection of human and animal health.

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Section: Discussionmentioning

confidence: 99%

Response of Fecal Bacterial Flora to the Exposure of Fumonisin B1 in BALB/c Mice

Zhang

Chen

Jiang

et al. 2021

Toxins

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“…Acute doses lead to liver necrosis, intrahepatic haemorrhage, and shock, whereas lower MC doses have been shown to lead to a slower onset of liver and kidney failure. MC exposure can also lead to mitochondrial alterations, affect intracellular calcium levels, and cause oxidative stress, all of which contribute to hepatotoxicity [ 24 ]. Since MCs pose severe health risks from both acute and chronic exposure, including hepatotoxicity [ 25 ] and nephrotoxicity [ 26 ], as well as cardiovascular toxicity [ 27 ] and even reproductive toxicity [ 28 ], it is imperative to ensure that human exposure is minimised; as such, their presence is monitored and regulated in a number of countries, including Australia [ 29 ], the USA [ 30 ], Norway [ 31 ], and many European countries [ 32 , 33 ].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Analysis of Cyanotoxins β-N-methylamino-L-alanine (BMAA) and Microcystins-RR, -LR, and -YR Using Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS)

Pravadali-Cekic,

Vojvodic,

Violi

et al. 2023

Molecules

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β-N-methylamino-L-alanine (BMAA) and its isomers, 2,4-diaminobutyric acid (2,4-DAB) and N-(2-aminoethyl)-glycine (AEG), along with microcystins (MCs)-RR, -LR, and -YR (the major MC congeners), are cyanotoxins that can cause detrimental health and environmental impacts during toxic blooms. Currently, there are no reverse-phase (RP) LC-MS/MS methods for the simultaneous detection and quantification of BMAA, its isomers, and the major MCs in a single analysis; therefore, multiple analyses are required to assess the toxic load of a sample. Here, we present a newly developed and validated method for the detection and quantification of BMAA, 2,4-DAB, AEG, MC-LR, MC-RR, and MC-YR using RP LC-MS/MS. Method validation was performed, assessing linearity (r2 > 0.996), accuracy (>90% recovery for spiked samples), precision (7% relative standard deviation), and limits of detection (LODs) and quantification (LOQs) (ranging from 0.13 to 1.38 ng mL−1). The application of this combined cyanotoxin analysis on a culture of Microcystis aeruginosa resulted in the simultaneous detection of 2,4-DAB (0.249 ng mg−1 dry weight (DW)) and MC-YR (4828 ng mg−1 DW). This study provides a unified method for the quantitative analysis of BMAA, its isomers, and three MC congeners in natural environmental samples.

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“…Cyanobacteria (formerly known as blue‐green algae) blooms occur in freshwater and saline ecosystems under certain environmental conditions, leading to eutrophication. Generally, these microorganisms are finely dispersed throughout the water, but they can produce considerable turbidity and can frequently release cyanotoxins into surface waters when they are concentrated at high densities 1 . These cyanotoxins are classified according to the mode of action in neurotoxins and hepatotoxins.…”

Section: Introductionmentioning

confidence: 99%

“…Animals and humans can be exposed to cyanotoxins when using surface water; there have been numerous reports of deaths of domestic animals caused by cyanotoxins produced by various species, such as Dolichospermum / Anabaena spp., Microcystis spp., Aphanizomenon spp., Oscillatoria spp., and Planktothrix spp 1‐3 . Cyanobacterial cell toxicity is also high, and animals can ingest a lethal dose by drinking just a few millilitres of water from surface accumulations on the banks 2 .…”

Section: Introductionmentioning

confidence: 99%

Clarification of cyanotoxins in El Guajaro Reservoir, Colombia using a microalgae‐based consortium MPMC

Gutiérrez

Gutiérrez-Hoyos²,

B³

et al. 2022

J of Chemical Tech & Biotech

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BACKGROUND Cyanobacteria blooms occur in freshwater and saline ecosystems under certain environmental conditions, such as eutrophication, that are often accompanied by the production of cyanotoxins; Those biological toxins are a risk to the health of animals and humans. The eutrophication of water bodies is becoming more frequent due to organic pollution pressure from swage discharge, so outcrops are frequent and difficult to manage by the communities affected by these phenomena. Most of the control mechanisms for these events are carried out through nutrient input constraints, sonication, and (more recently) biological control. RESULTS In this work, a cyanobacterial bloom in a reservoir in a tropical zone of northern Colombia was characterized. The microbiological dominance of Microcystis sp. and the presence of microcystin in the water were documented. A bioaugmentation process was then tested with a microbial consortium containing a predominance of microalgae (MCPM); after this, the dominance of cyanobacteria was broken and the richness and density of the phytoplankton were recovered. The decrease in cyanobacterial density was documented 15 days after the MCPM bioaugmentation began. A significant removal (34% to 53%) of Microcystis sp, was observed between days 1 and 16; from day 16 to day 58, removal of Microcysis sp reached 92% to 100%. The bioaugmentation took a total of 58 days. CONCLUSION This work raises the possibility of using the competitive inhibition capacity of nonharmful microalgae on cyanobacteria as an ecological tool to counteract blooms and mitigate the risk of cyanotoxins for animals and humans. © 2021 Society of Chemical Industry (SCI).

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Cyanobacteria

Cited by 5 publications

References 42 publications

Response of Fecal Bacterial Flora to the Exposure of Fumonisin B1 in BALB/c Mice

Response of Fecal Bacterial Flora to the Exposure of Fumonisin B1 in BALB/c Mice

Simultaneous Analysis of Cyanotoxins β-N-methylamino-L-alanine (BMAA) and Microcystins-RR, -LR, and -YR Using Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS)

Clarification of cyanotoxins in El Guajaro Reservoir, Colombia using a microalgae‐based consortium MPMC

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