Cyanoacrylate for Wound Closure in Prosthetic Vascular Graft Surgery to Prevent Infections Through Contamination

Aksoy, Murat; Turnadere, Erhan; Ayalp, Kemal; Kayabali, Murat; Ertuğrul, Mustafa Bülent; Bilgic, Levent

doi:10.1007/s00595-005-3095-3

Cited by 15 publications

(12 citation statements)

References 16 publications

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“…[ [4][5][6][7][8][9][10][11][12][13] Second, since cyanoacrylate closes the wound mechanically, bleeding is reduced and its effect is independent of the patient's hemostatic function. This may be of particular importance for diabetic patients with atherosclerotic or fragile vessels.…”

Section: Discussionmentioning

confidence: 99%

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2 octyl-cyanoacrylate glue for Fixation of STSG in genitourinary tissue defects due to Fournier gangrene: A Preliminary Trial

Sivrioğlu¹,

Irkoren²,

Ceylan³

et al. 2013

Ulus Travma Acil Cerrahi Derg

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Section: Discussionmentioning

confidence: 99%

“…The use of tissue adhesive overcomes these problems. [4][5][6][7][8][9][10][11][12][13] Last, for the directed usage, the cost of cyanoacrylate sealant is lower than most other sealants and conventional suture methods.…”

Section: Discussionmentioning

confidence: 99%

2 octyl-cyanoacrylate glue for Fixation of STSG in genitourinary tissue defects due to Fournier gangrene: A Preliminary Trial

Sivrioğlu¹,

Irkoren²,

Ceylan³

et al. 2013

Ulus Travma Acil Cerrahi Derg

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“…Aksoy et al [20] have shown that cyanoacrylates act as a barrier against microbial penetration and serve as an optimal wound dressing, creating a moist environment to enhance wound healing. In this study, the amount of perivascular inflammatory tissue after anastomosis and neointimal hyperplasia with N-butyl-2-cyanoacrylate was less than that with sutures only.…”

Section: Discussionmentioning

confidence: 99%

Sutureless Vascular Anastomoses by N-Butyl-2 Cyanoacrylate Adhesive: An Experimental Animal Study

Saba¹,

Yılmaz²,

Yavûz³

et al. 2007

Eur Surg Res

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Background: The purpose of this animal study was to find out whether sutureless anastomoses using N-butyl-2-cyanoacrylate were effective in the suppression of neointimal hyperplasia or not. Material and Methods: Ten male adult mongrel dogs were used in this animal study. The animals were randomly divided into a control group (n = 5) and a study group (n = 5). The study group underwent sutureless anastomoses using N-buthyl-2-cyanoacrylate adhesive. Infrarenal aortoaortic graft was interposed using polytetrafluoroethylene. Results: In the study group, the mean intimal thickness at the proximal anastomosis was 27.4 ± 1.94 µm and 27.4 ± 1.51 µm at the distal anastomosis. In the control group, the mean intimal thickness was 138.4 ± 5.02 µm at the proximal anastomosis and 67.6 ± 6.42 µm at the distal anastomosis. Intimal thickness at the proximal and distal anastomoses in the control group was significantly (p < 0.001) greater than in the study group. Also, perianastomotic inflammation was more obvious in the control group compared to the study group (p < 0.01). Conclusion: Sutureless anastomoses using with N-butyl-2-cyanoacrylate adhesive might be a good alternative to conventional suture technique.

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“…A liquid cyanoacrylate-based, microbial sealant has been designed as an adhesive skin barrier to seal residual bacteria on the skin and prevent bacterial contamination in surgical wounds. In one animal model [1] topical cyanoacrylate reportedly decreased bacterial contamination of the wound from the outside and in another animal model [3] cyanoacrylate microbial sealant decreased bacterial skin contaminations of surgical wounds compared with adhesive iodine-barrier drapes. In two studies, this type of Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.…”

Section: Introductionmentioning

confidence: 97%

Cyanoacrylate Microbial Sealant May Reduce the Prevalence of Positive Cultures in Revision Shoulder Arthroplasty

Lorenzetti

Wongworawat

Jobe

et al. 2013

Clinical Orthopaedics &Amp; Related Research

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Background Cyanoacrylate-based, microbial sealant is an adhesive skin barrier designed to prevent bacterial contamination in surgical wounds. This type of adhesive barrier could have use in decreasing the incidence of positive cultures and subsequent infection in shoulder arthroplasty. Questions/purposes We therefore evaluated whether cyanoacrylate microbial sealant reduced the positive intraoperative culture rates in revision shoulder arthroplasty. Methods We retrospectively reviewed 55 patients who underwent revision shoulder arthroplasties. Intraoperative aerobic and anaerobic deep tissue culture results taken during the revisions were compared. Cultures were taken of the deep synovial tissue lining the prosthesis. Patients were divided into two groups: those who underwent standard preparations with adhesive, iodine-barrier drapes (Group SP) and those who had placement of cyanoacrylate microbial sealant in addition to the standard prep (Group MS). Results The prevalence of cases with positive cultures was 18% (seven of 40) in Group SP compared with 7% (one of 15) in Group MS. The prevalence of positive, anaerobic Propionibacterium acnes cultures was 13% in Group SP compared with 7% in Group MS. The prevalence of infections confirmed at revision surgery was 8% in Group SP versus 0% in Group MS. Conclusions Our observations suggest application of a cyanoacrylate microbial sealant may reduce the prevalence of positive cultures and thereby subsequent infections in revision shoulder arthroplasties.

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Cyanoacrylate for Wound Closure in Prosthetic Vascular Graft Surgery to Prevent Infections Through Contamination

Cited by 15 publications

References 16 publications

2 octyl-cyanoacrylate glue for Fixation of STSG in genitourinary tissue defects due to Fournier gangrene: A Preliminary Trial

2 octyl-cyanoacrylate glue for Fixation of STSG in genitourinary tissue defects due to Fournier gangrene: A Preliminary Trial

Sutureless Vascular Anastomoses by N-Butyl-2 Cyanoacrylate Adhesive: An Experimental Animal Study

Cyanoacrylate Microbial Sealant May Reduce the Prevalence of Positive Cultures in Revision Shoulder Arthroplasty

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