Cyanoacrylate as a retrofilling material

Barkhordar, Rahmat A.; Javid, Bahram; Abbasi, Jan; Watanabe, Larry G.

doi:10.1016/0030-4220(88)90362-3

Cited by 19 publications

(17 citation statements)

References 25 publications

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“…Such tissue response was expected in our study, as many authors have shown similar or same results on experimental animal tissue on implanted sealers based on epoxy resins (Smith and Smith, 1968;Alvas, 1982;Barkhordar et al, 1988;DiFelice and Lombardi, 1998;Ahlberg and Tay, 1996;Vujaskovi}, 1999;Bernath and Szabo, 2003).…”

Section: Discussionsupporting

confidence: 88%

“…Most of them have shown low citotoxicity of calcium hydroxide based materials (Zmener, 1981;Barkhordar et al, 1988;Matsumoto et al, 1989;Weine, 1989;Takahara et al, 1990;Leinenbach et al, 1993;Spangberg et al, 1993;Mittal et al, 1995;Vairabhaya et al, 1997;DiFelice and Lombardi, 1998;Leonardo et al, 1999;Bernath and Szabo, 2003;, which our study does not support.…”

Section: Discussioncontrasting

confidence: 71%

“…Cyano-acrilic cements (McComb and Smith, 1976;Torabinejad et al, 1984;Barkhordar et al,1988;Smith and Smith, 1993), Poly-HEMA (Hydron, NPD dental systems INC, New Brunchwire, NY) - (Weine, 1989) and bone cements PMMA based (Heeley and Tomic, 1981;Linden et al, 1981;Karadzic 1999Karadzic , 2001Karadzic , 2004 and PEMA -polyethil metacrylate (Ahlberg and Tay, 1996), are materials for root canal obturation, which showed high tolerancy to human periapical tissue. Cyano-acrilic cements (McComb and Smith, 1976;Torabinejad et al, 1984;Barkhordar et al,1988;Smith and Smith, 1993), Poly-HEMA (Hydron, NPD dental systems INC, New Brunchwire, NY) - (Weine, 1989) and bone cements PMMA based (Heeley and Tomic, 1981;Linden et al, 1981;Karadzic 1999Karadzic , 2001Karadzic , 2004 and PEMA -polyethil metacrylate (Ahlberg and Tay, 1996), are materials for root canal obturation, which showed high tolerancy to human periapical tissue.…”

Section: Introductionmentioning

confidence: 99%

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Biocompatibility of root canal obturation materials implanted in rats muscular tissue

Karadzic¹,

Vujaskovic²

2009

Acta vet. (Beogr.)

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The purpose of this study was to investigate the biocompatibility of different dental materials for teeth root canal obturation, implanted in rat muscular tissue, by analyzing the type of muscular tissue inflammatory reaction level. In the preparation of Wistar rats M. biceps femoris, three different materials for root canal obturation were implanted: Sealapex (Kerr, Romulus, USA), AH-26 (DE Trey, Zurich, Switzerland) and Spongio cement material based on polymethil metacrylate - PMMA (Tomić, 1981, US patent 4296209). The used control material was sterile wax. The rats were sacrificed 30 and 60 days after implantation and the response of the tissue on implanted material was evaluated with standard histological methods on 6 _m sections stained with hematoxilin and eosin. Implantation of Sealapex in rat muscle tissue produced a strong acute inflammation, infiltration with massive polymorphonuclear and numerous giant cells. Acute inflammation still persisted 60 days after implantation. AH-26 produced a strong reaction around the alien body with predominantly limphocitic infiltration. Giant cells and macrophages contained phagocited pieces of material. After 60 days expressive chronic myositis was present with a mass of giant cells and proliferation of connective tissue. Thirty days later the results of histological investigations suggested that implanted PMMA based material still produced a connective fibrous capsula made of fibroblasts and fibrocytes around the implanted material. In the muscular tissue myositis developed forming granulomatous tissue. After 60 days a capsula was made of mature hyalinisated connective tissue without signs of inflammation in the surrounding muscular tissue. The reaction is similar to the reaction to inert control material, such as sterile wax. These findings suggest biocompatibility of PMMA based material for canal obturation

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Section: Discussionsupporting

confidence: 88%

Section: Discussioncontrasting

confidence: 71%

Section: Introductionmentioning

confidence: 99%

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Biocompatibility of root canal obturation materials implanted in rats muscular tissue

Karadzic¹,

Vujaskovic²

2009

Acta vet. (Beogr.)

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“…Cyanoacrylate has been used in dentistry as dental filling or bonding material with improved affinity for the tooth for many years (21). However, the effect of cyanoacrylate-based filling materials on PDL fibroblast survival and its cytotoxic effect mechanisms are not fully understood.…”

Section: Discussionmentioning

confidence: 99%

Cytotoxic Effects of Four Different Endodontic Materials in Human Periodontal Ligament Fibroblasts

Avcu

Görduysus

Pekel

et al. 2007

Journal of Endodontics

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“…1 It has been proved by many studies that these adhesives can be safely used in sutures, [2][3][4][5][6] as well as for pulp capping, 7 and retrofilling material in endodontic surgeries. [8][9][10] Their use is recommended for their hemostatic and antiinflammatory features and also for their high adhesion ability in a moist environment.…”

Section: Introductionmentioning

confidence: 99%

In vivo qualitative analysis of the biocompatibility of different cyanoacrylate-based adhesives

et al. 2008

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Cyanocrylates have been widely used in the medical and dental fields for several years. In Dentistry, cyanoacrylates have been used for suturing, pulp capping, as retrofilling material in endodontic surgeries, and as cervical plug for pulpless teeth bleaching. The biocompatibility of these adhesives has been the topic of many researches and subcutaneous implantation is an effective methodology for these studies. The present study evaluated the biocompatibility of three different cyanoacrylate-based adhesives. Thirty-six Wistar rats were used, divided into four groups of 9 animals each: A (control) -distilled water, B -cyanoacrylate ester (Super Bonder), C -n-butyl-cyanoacrylate (Histoacryl) and D -alpha-cyanoacrylate (Three Bond). The materials were dispensed in sponges of polyvinyl chloride, the animals were incised and the sponges were inserted in the subcutaneous tissue and sutured. Each group was sub-divided according to the time of sacrifice of the animals: 7, 21 and 45 days. Subjective analysis of the histologic material showed that all groups presented some degree of irritability, but the inflammatory reaction decreased with the experimental time in all groups. Group D showed an inflammatory reaction which was closer to that of the control group and was considered to have good biocompatibility. Groups B and C were similar and presented more aggressive inflammatory reactions when compared to the control group. Based on the results, it was concluded that alpha-cyanoacrylate (Three Bond) was the most biocompatible adhesive because it caused the lowest levels of inflammation.

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Cyanoacrylate as a retrofilling material

Cited by 19 publications

References 25 publications

Biocompatibility of root canal obturation materials implanted in rats muscular tissue

Biocompatibility of root canal obturation materials implanted in rats muscular tissue

Cytotoxic Effects of Four Different Endodontic Materials in Human Periodontal Ligament Fibroblasts

In vivo qualitative analysis of the biocompatibility of different cyanoacrylate-based adhesives

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