Cutting and Skin‐Ablative Properties of Pulsed Mid‐Infrared Laser Surgery

Kaufmann, Roland; Hartmann, Anke; Hibst, Raimund

doi:10.1111/j.1524-4725.1994.tb00123.x

Cited by 174 publications

(81 citation statements)

References 19 publications

(25 reference statements)

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“…Carbon dioxide laser removal, in contrast, even in pulsed modes, can produce cumulative necrosis after serial pulsing (usually more than 3 passes) owing to tissue desiccation with loss of absorbing water on the irradiated surface. 18,19 Therefore, thermal laser vaporization and electrodesiccation are limited in deeper lesions, where a risk of hypertrophic scar or keloid formation has to be considered. We did not observe the development of hypertrophic scars in our patients, which was reported to occur after carbon dioxide laser vaporization in a patient with familial benign chronic pemphigus.…”

Section: Commentmentioning

confidence: 99%

“…In contrast, erbium:YAG laser ablation, operating at a wavelength of 2.94 µm, combines the most efficacious stepwise etching of the skin surface with the least thermal damage owing to its unique absorption characteristics in tissue water. 18,19 This technique should therefore allow the precisely controlled removal of lesions in both HHD and DD and limit the injury in widespread lesions or in those located on areas prone to keloid formation. We decided to treat 4 patients (2 with HHD and 2 with DD) with pulsed 2.94-µm erbium:YAG laser ablation and found this approach to be of special advantage in patients with DD.…”

mentioning

confidence: 99%

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Efficacy of Erbium:YAG Laser Ablation in Darier Disease and Hailey-Hailey Disease

Beier¹,

Kaufmann²

1999

Arch Dermatol

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108

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Background: Among different surgical approaches, dermabrasion and carbon dioxide laser vaporization have been used to treat Hailey-Hailey disease (HHD) (familial benign chronic pemphigus) and Darier disease (DD) (keratosis follicularis), with various results. Because of the erbium: YAG laser's unique absorption characteristics in tissue water, erbium:YAG laser ablation combines the advantages of both techniques, avoiding thermal injury of vaporization and also allowing selectively deeper tissue removal in the follicular lesions of DD. Therefore, good results should be expected in both types of acantholytic disorders.Observations: Four patients (2 with HHD and 2 with DD) with different affected areas were treated with laser ablation. During a follow-up period ranging from 8 to 20 months, complete remission was achieved in 3 patients-2 with DD and 1 with HHDand significant improvement was achieved in 1 patient with HHD. Histological examination of control biopsy specimens after ablation in 1 patient with DD revealed no signs of the disease and only a slight fibrosis in the papillary dermis.Conclusions: Erbium:YAG laser ablation effectively removes lesions of both HHD and DD and can also yield excellent long-term results in chronic, recalcitrant cases.

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Section: Commentmentioning

confidence: 99%

mentioning

confidence: 99%

Efficacy of Erbium:YAG Laser Ablation in Darier Disease and Hailey-Hailey Disease

Beier¹,

Kaufmann²

1999

Arch Dermatol

Self Cite

108

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“…The ex-vivo pig skin experiments verified the accuracy and reliability of this model. In the reason of that pig skin has been widely used in the study of infrared laser surgery and its thermal properties have been verified, a more precise prediction of temperature distributions thereby can be utilized as a reference for selecting laser powers in the study of LEPs [17,22]. Moreover, there are some new findings in this study.…”

Section: Discussionmentioning

confidence: 87%

Temporal and spatial temperature distributions on glabrous skin irradiated by a 1940 nm continuous-wave laser stimulator

Yang

Dong

et al. 2015

Biomed. Opt. Express

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For predicting pain stimulation effects and avoiding damage in 1940nm laser evoked potentials (LEPs) experiments, a 2-layer finite element model (FEM-2) was constructed. A series of experiments were conducted on ex-vivo pig skin pieces to verify temperature distribution predicted by this model. Various laser powers and beam radii were employed. Experimental data of time-dependent temperature responses in different sub-skin depths and space-dependent surface temperature was recorded by thermocouple instrument. By comparing with the experimental data and model results, FEM-2 model was proved to predict temperature distributions accurately. A logarithmic relationship between laser power density and temperature increment was revealed by the results. It is concluded that power density is an effective parameter to estimate pain and damage effect. The obtained results also indicated that the proposed FEM-2 model can be extended to predict pain and damage thresholds of human skin samples and thus contribute to LEPs study.

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“…[13][14][15][16][17][18][19]27 However, the continuous-wave and superpulse CO 2 laser were limited by their thermal effects. Improvements in laser technology by use of the theory of selective photothermolysis have enabled the use of pulsed laser systems which minimize thermal damage to noninvolved tissue.…”

Section: Discussionmentioning

confidence: 99%