Cutaneous Waldenstr?m's macroglobulinemia: Report of a case and overview of the spectrum of cutaneous disease

Libow, Lester F.; Mawhinney, Jeffrey P.; Bessinger, G. Todd

doi:10.1067/mjd.2001.103262

Cited by 50 publications

(44 citation statements)

References 24 publications

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“…4 Other non-specific cutaneous features, such as Schnitzler's syndrome, xanthoma disseminated, amyloid deposition, paraneoplastic pemphigus, and urticaria, could be observed in WM. 5 Specific cutaneous manifestations may be subdivided into two categories comprising (1) specific …”

Section: Discussionmentioning

confidence: 99%

“…The lesions may occur either during the evolution of the disease or may sometimes represent the initial feature revealing the disease. 9 Lesions are generally reddish-brown or violaceous in colour and may be either macular, 10 papulonodular, 11,12 or infiltrated plaques, 5,11 localized mainly on the face or the trunk.…”

Section: Manifestations In Relation To Igm Deposits and (2) Cutaneousmentioning

confidence: 99%

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Cutaneous Waldenström's macroglobulinemia with “deck-chair” sign treated with cyclophosphamide

Autier¹,

Buffet²,

Pinquier

et al. 2005

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 99%

Section: Manifestations In Relation To Igm Deposits and (2) Cutaneousmentioning

confidence: 99%

Cutaneous Waldenström's macroglobulinemia with “deck-chair” sign treated with cyclophosphamide

Autier¹,

Buffet²,

Pinquier

et al. 2005

Journal of the American Academy of Dermatology

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“…Skin signs may either precede or follow the diagnosis. Prognosis does not appear to be influenced by the presence or absence of cutaneous disease [1]. …”

Section: Discussionmentioning

confidence: 99%

Waldenström macroglobulinaemia presenting as tingling ulcers on the feet

Fischer

Dyall‐Smith

Peters

et al. 2013

Dermatol Pract Concept

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A 56-year-old man presented with tingling ulcers on the feet. On further skin examination, papules on the knees were observed. Biopsies revealed extravascular eosinophilic deposits of IgM, and Waldenström macroglobulinaemia was diagnosed. The skin manifestations have resolved with chemotherapy. Peripheral neuropathy and storage papules are rare manifestations of Waldenström’s macroglobulinaemia.

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“…Secondary involvement of the skin is a rare complication of Waldenström's macroglobulinemia (9). In the present report, the cutaneous lesions were clinically interpreted as being due to WM.…”

Section: Discussionmentioning

confidence: 99%

Lymphomatoid Papulosis in a Patient with Waldenström's Macroglobulinemia

Ribeiro‐Silva

Chang

Arruda

et al. 2005

The Journal of Dermatology

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Lymphomatoid papulosis (LyP) is a rare skin disease with a benign course but a malignant histologic appearance based on atypical lymphocytes. Waldenström's macroglobulinemia (WM) is a diffuse infiltration of the bone marrow by cells that synthesize IgM immunoglobulins. A 46-year-old female presented with a two year history of weakness, fatigue, anemia, and recurring multiple erythematous papules and nodules in the skin. The skin biopsy showed pleomorphic lymphoid cells with atypical mitoses permeated by a diffuse dermal infiltrate of normal appearing lymphocytes. The neoplastic cells were positive for CD30, CD3, and CD5 but negative for CD20 and EMA. The bone marrow was hypercellular due to a diffuse infiltration by lymphocytes, plasma cells, and plasmacytoid lymphocytes. LyP is a lymphoproliferative disorder of CD30-positive T cells that may be associated with other lymphoid malignancies, particularly Hodgkin's disease, mycosis fungoides, and anaplastic T cell lymphomas. To our knowledge, this is the first report of a LyP appearing in a patient with WM.

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Cutaneous Waldenstr?m's macroglobulinemia: Report of a case and overview of the spectrum of cutaneous disease

Cited by 50 publications

References 24 publications

Cutaneous Waldenström's macroglobulinemia with “deck-chair” sign treated with cyclophosphamide

Cutaneous Waldenström's macroglobulinemia with “deck-chair” sign treated with cyclophosphamide

Waldenström macroglobulinaemia presenting as tingling ulcers on the feet

Lymphomatoid Papulosis in a Patient with Waldenström's Macroglobulinemia

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