2011
DOI: 10.1016/j.farmae.2010.10.001
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Cutaneous Toxicity Associated With Cetuximab Treatment in Metastatic Colorectal Cancer

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“…It is related to the inhibition of EGFR in the skin, which is crucial for the normal development and phys-iology of the epidermis 1 . Several trials have shown a positive relationship between skin toxicity, response rate and overall survival in patients receiving cetuximab, and found that skin toxicity was a predictor of response to cetuximab 8,9 . Other cutaneous reactions to cetuximab are xerosis, painful fissures in the palms and soles, alterations in hair growth, and mucositis 10 .…”
Section: Introductionmentioning
confidence: 99%
“…It is related to the inhibition of EGFR in the skin, which is crucial for the normal development and phys-iology of the epidermis 1 . Several trials have shown a positive relationship between skin toxicity, response rate and overall survival in patients receiving cetuximab, and found that skin toxicity was a predictor of response to cetuximab 8,9 . Other cutaneous reactions to cetuximab are xerosis, painful fissures in the palms and soles, alterations in hair growth, and mucositis 10 .…”
Section: Introductionmentioning
confidence: 99%