Cutaneous squamous cell carcinoma in Calabar, southern Nigeria

Asuquo, Maurice E.; Udosen, A M; Ikpeme, I. A.; Ngim, Ne; Otei, O. O.; Ebughe, Godwin; Bassey, E. E.

doi:10.1111/j.1365-2230.2009.03243.x

Cited by 24 publications

(30 citation statements)

References 7 publications

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“…This difference is due to genetically pigmented skin of our patients whose dense epidermal melanin protects them from ultraviolet radiation [11], and therefore, preventing them from skin cancers. In the present study, Kaposi sarcoma was the most common cancer which is similar to that of several Subsaharian African studies [12,13] and different from that of developed country studies in which basal cell carcinoma was the most prevalent [3][4][5].…”

Section: Discussionsupporting

confidence: 54%

Skin pathology of the elderly patients: Case of black African

Diabaté¹,

Kourouma²,

Vagamon³

et al. 2018

Our Dermatol Online

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Section: Discussionsupporting

confidence: 54%

Skin pathology of the elderly patients: Case of black African

Diabaté¹,

Kourouma²,

Vagamon³

et al. 2018

Our Dermatol Online

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“…This is similar to reports from Zaria [11], Jos [12], Kano [10], and Uganda [13], but differs from Calabar [14] and Zimbabwe [15] who reported Kaposi sarcoma was their commonest cutaneous malignancy. The most prevalent site is the lower limb (Table 2), and this finding is similar to reports from Nigeria [10][11][12][13][14] and Tanzania [4]. While sun exposure is the major aetiological factor in Whites, chronic ulcers and inflammation appear to be leading risk factor in Blacks.…”

Section: Discussionsupporting

confidence: 89%

“…Two cases (5%) of basal cell carcinoma were found in this study. Literature search on the reviews of cutaneous malignancies revealed that basal cell carcinoma is uncommon in Africans because of the protective skin pigmentation from UV radiation [8][9][10][11][12][13][14]. Our findings are comparable to reports from other parts of Nigeria [8][9][10][11][12][13][14].…”

Section: Discussionsupporting

confidence: 78%

Cutaneous Malignancies Presenting as Superficial Ulcers

Peter¹,

Ahmed²,

Ademola³

et al. 2014

UCMS

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Epidermal skin cancers are the most common cancers in humans. Epidermal skin cancers present a unique opportunity for effective intervention with both early detection and primary prevention. They are amenable to clinical diagnosis by simple visual inspection and to pathologic diagnosis by minimally invasive biopsy. Our objective is to show that the cutaneous malignancies are common in our environment and frequently present as superficial ulcer. This is a 4-year retrospective histopathological analysis of cutaneous malignancies diagnosed between January 2006 and December 2009 in the Department of Pathology, Federal Medical Centre, Keffi, Nasarawa State. The specimens were fixed in 10% buffered formalin, processed in paraffin wax and stained with haematoxylin and eosin. The slides were studied and the lesions were characterized by two consultant pathologists who were blinded and they agreed on the diagnosis. Twenty-one cases were reviewed in this analysis. The age range was between 20-79 years old with the mean age of 59.5 years old. The male to female ratio was 1.1:1. The peak age of distribution was in the fourth decade. In this review, the most common malignancy was squamous cell carcinoma; followed by malignant melanoma and basal cell carcinoma. The lower extremity was the commonest site with 11 (52.2%) cases; this was followed by the head and neck region with 7 (33.1%) cases, while one (4.7%) case with each presented in the anterior chest wall, elbow and at an unspecified site. Cutaneous malignancies are common in our environment; and the early sign is that of chronic non-healing ulcer. So there is need for high index of suspicion on the part of the Clinicians and Pathologists. Early identification of high-risk lesions can allow for more rapid therapeutic intervention, reducing the likelihood of metastasis and death.

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“…7,16,17 However, studies in Calabar documented that Kaposi Sarcoma was the commonest malignancy, while melanomas were the most frequent in Benin and Tanzania. 6,12,15 In addition basal cell carcinomas were the most common skin malignancy in the United States, China and Egypt, while they accounted for only 7.1% of cancers diagnosed in this study. 18,19 These variations are due to difference in skin types amongst the different racial groups.…”

Section: Discussionmentioning

confidence: 99%

Dermatologic neoplasms: a perspective from Makurdi, North Central Nigeria

Ajetunmobi

Dzuachii

2017

Int J Res Dermatol

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Background: Skin cancers are the commonest malignancies in Caucasians but are relatively less common in dark skinned persons. They are strongly linked to ultraviolet exposure, skin melanin content, and immune status.Methods: This study reviewed all histologically diagnosed skin neoplasms at the Federal Medical Centre, Makurdi from January 2012 to December 2016.Results: A total of 84 neoplasms were seen, with 42 (50%) being malignant. Of the malignant lesions, Squamous cell carcinomas were the most frequent (45.2%), followed by melanomas (23.8%). The lower limb was the most frequent site of both benign and malignant neoplasms, while a male to female ratio of 0.88:1 was observed.Conclusions: A relatively high UV radiation intensity, combined with a predominance of outdoor agricultural based activities, alongside chronic ulcerative/inflammatory lesions and a high HIV burden all indicate a need for widespread enlightenment and screening campaigns to prevent occurrence of skin cancers and aid early diagnosis.

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Cutaneous squamous cell carcinoma in Calabar, southern Nigeria

Cited by 24 publications

References 7 publications

Skin pathology of the elderly patients: Case of black African

Skin pathology of the elderly patients: Case of black African

Cutaneous Malignancies Presenting as Superficial Ulcers

Dermatologic neoplasms: a perspective from Makurdi, North Central Nigeria

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