Cutaneous smooth muscle tumors associated with Epstein-Barr virus in an adult patient with HIV

Piedrahita, Estefania Galeano; Maya-Rico, Ana María; Suárez, Ana Cristina Ruiz; Walter, Andrea Laverde

doi:10.1016/j.abd.2020.06.010

Cited by 2 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A study by Deyrup et al examined EBV-SMTs in 19 patients with multiorgan involvement and found that, in each case, the tumors were genetically distinct, suggesting that the multiorgan condition arises from multiple primary tumors rather than metastasis [59]. Moreover, it has been observed that EBV-SMTs related to HIV infection tend to have a higher likelihood of central nervous system involvement [25][26][27]29,31,35,43,45,52,59].…”

Section: Ebv-associated Smooth Muscle Tumorsmentioning

confidence: 99%

A Clinicopathology Review and Update of Epstein–Barr Virus-Associated Mesenchymal Tumors

Lee,

Omar,

Tay

et al. 2023

Cancers

View full text Add to dashboard Cite

The Epstein–Barr virus (EBV) is associated with various tumor types, including nasopharyngeal carcinoma and lymphoproliferative disorders. While much is known about EBV-related epithelial and lymphoid tumors, there is a paucity of knowledge concerning EBV-associated mesenchymal tumors. This review aims to provide a comprehensive overview of EBV-associated mesenchymal tumors, encompassing their clinical features, pathological characteristics, pathophysiology, prognostic factors, and current treatment approaches. Through an extensive literature search using the PubMed database, we were able to identify three distinct EBV-associated mesenchymal tumors: EBV-associated smooth muscle tumors, inflammatory pseudotumor-like follicular dendritic cell sarcomas, and EBV-associated osteosarcomas. Although this review extensively explored the different aspects of these mesenchymal tumors, our comprehension of the underlying pathophysiology in this context is still incomplete. Therefore, we hope that this review paper will not only serve as a valuable repository of information but also serve as a catalyst for prospective in vitro and in vivo research studies to bridge the existing knowledge gap surrounding pathophysiology, ultimately making an important contribution to shaping future therapeutic approaches.

show abstract

Section: Ebv-associated Smooth Muscle Tumorsmentioning

confidence: 99%

A Clinicopathology Review and Update of Epstein–Barr Virus-Associated Mesenchymal Tumors

Lee,

Omar,

Tay

et al. 2023

Cancers

View full text Add to dashboard Cite

show abstract

HIV and the Skin

Bunker,

Piguet

2024

Rook's Textbook of Dermatology

View full text Add to dashboard Cite

Within 2 years of defining acquired immune deficiency syndrome (AIDS) as a distinctive syndrome in 1981, human immunodeficiency virus (HIV) was identified as the causative agent. Dermatological involvement in AIDS has been appreciated since the disease was first recognised. Mucocutaneous involvement establishes criteria for diagnosis and staging; the prognostic significance of some complications, for example pruritic papular eruption/eosinophilic folliculitis, hairy leukoplakia and Kaposi sarcoma (KS), was well recognised before specific treatments were introduced. The proportion of patients with skin complications and the number of these manifestations in any one patient increase as HIV infection progresses and AIDS develops. The incidence and severity of several common cutaneous diseases (such as mollusca, herpes simplex and seborrhoeic dermatitis) are increased in patients with HIV and this correlates in many instances with the absolute numbers of CD4+ T cells. The effect HIV infection may have on some dermatological conditions such as psoriasis and leprosy is less clear‐cut. The advent of highly active combined antiretroviral therapy (ART) has been incalculably beneficial to patients with HIV, but novel side effects of these drugs (such as lipodystrophy) have emerged, and the skin can be affected by manifestations of the immune reconstitution inflammatory syndrome/immune reconstitution associated disease. The dermatological complications of HIV and AIDS may be distressing to patients and difficult for dermatologists to diagnose and manage. Also, many dermatoses presenting in the population at large need to be regarded as ‘indicator conditions’ to prompt advice about, and initiation of, HIV testing.

show abstract

Cutaneous smooth muscle tumors associated with Epstein-Barr virus in an adult patient with HIV

Cited by 2 publications

References 9 publications

A Clinicopathology Review and Update of Epstein–Barr Virus-Associated Mesenchymal Tumors

A Clinicopathology Review and Update of Epstein–Barr Virus-Associated Mesenchymal Tumors

HIV and the Skin

Contact Info

Product

Resources

About