Cutaneous Silicone Granuloma Mimicking Breast Cancer after Ruptured Breast Implant

El-Charnoubi, Waseem Asim Ghulam; Henriksen, Trine; Elberg, Jens Jørgen

doi:10.1155/2011/129138

Cited by 5 publications

(9 citation statements)

References 14 publications

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“…A comprehensive literature review was performed using PubMed and MEDLINE to include all cases of siliconomas mimicking breast cancer ( Table 1 ). 13 cases were identified including this one [ 4 , [6] , [7] , [8] , [11] , [12] , [13] , [14] , [15] , [16] ]. Siliconomas developed 4 weeks to 16 years following rupture.…”

Section: Discussionmentioning

confidence: 99%

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Giant siliconoma mimicking locally advanced breast cancer: A case report and review of literature

Carson

Cox²,

Ismael³

2018

International Journal of Surgery Case Reports

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HighlightsSiliconomas of the breast develop as a result of implant rupture and present with many of the signs and symptoms of breast cancer.MRI is the preferred study for diagnosis and a preoperative tissue sample should be attempted.We present a patient with a giant breast siliconoma and perform a comprehensive literature review.Our patient underwent a modified radical mastectomy with delayed closure.The majority of patients should undergo surgery due to symptoms or the inability to rule out cancer.

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Section: Discussionmentioning

confidence: 99%

“…US-guided core biopsy revealed SG. None High SG El-Charnoubi et al [ 14 ] 2011 1 60 13 Unknown Painful mass with growth over 7-8 years. Patient presents again 3 months after initial workup/surgery with new tumor and erosion of overlying breast tissue.…”

Section: Discussionmentioning

confidence: 99%

Giant siliconoma mimicking locally advanced breast cancer: A case report and review of literature

Carson

Cox²,

Ismael³

2018

International Journal of Surgery Case Reports

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“…Once an implant ruptures, free silicone can migrate. Most frequently free silicone infiltrates the adjacent breast tissues and sometimes can mimic breast cancer [ 5 , 6 ]. The second most common place for free silicone migration is regional lymph nodes (axillary lymph nodes), and silicone aggregates in lymph nodes can also mimic malignant processes [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

The Value of Ultrasound in the Evaluation of the Integrity of Silicone Breast Implants

et al. 2021

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Background and Objective: Breast implant surgery for cosmetic purposes is the most popular plastic surgery and it has been performed for over 100 years. Rupture of silicone gel-filled breast implants usually is asymptomatic and is one of the more dangerous complications due to free silicone migration. The aim of our study was to evaluate the diagnostic value of ultrasound (US) in the evaluation of the integrity of silicone breast implants and identify the main sign of intact and ruptured breast implants. Patients and Methods: In this retrospective study, the medical documentation of women who underwent breast implant surgery and US checkups at Tautrimas Aštrauskas Clinic in Kaunas, Lithuania, during 2015–2020 was analyzed. The patients were divided into two groups: patients with intact and ruptured breast implants. The accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) as well as the signs of implant integrity of US examination were evaluated. Results: In this study, 76 women with bilateral breast implants (n = 152) were reviewed. On a US examination, ruptured implants were found in 41.1% (n = 61) of the cases; of them, 78.7% (n = 48) of the cases had ≥2 US signs of a ruptured implant, and in all these cases, implant rupture was confirmed at surgery. Overall, one US sign of a ruptured implant was found in 21.3% (n = 13) of the cases. Of them, inhomogeneous content in all cases (n = 3) was found in the intact implant group, and an abnormal implant shell was documented more often in the ruptured implant group, not intact one (n = 9, 90% vs. n = 1, 10%). US had a diagnostic accuracy of 94.7%, sensitivity of 98.3%, specificity of 89.2%, PPV of 93.4%, and NPV of 97.1% in the evaluation of implant integrity. Conclusions: Our results show that US is a very reliable alternative in evaluating breast implant integrity and could be the investigation of choice for implant rupture, while MRI could be advocated only in inconclusive cases. Uneven implant shell was found to be the most important US sign of breast implant rupture. Based on the findings, we recommend performing US examination after breast augmentation surgery with silicone gel-filled implants annually.

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“…La formación de siliconomas es una de las posibles complicaciones de la inyección de siliconas líquidas con fines cosméticos, o cuando los implantes mamarios se rompen y permiten la fuga de gel de silicona (5) . En 1964, Winer, et al, informaron el primer caso de siliconoma, causado por la inyección de silicona líquida para aumento mamario y como relleno facial; posteriormente, en 1980, se describió en relación con la ruptura de implantes mamarios (6)(7)(8) . Esta última situación adquirió creciente importancia después de la problemática desencadenada por los implantes Poly Implant Prothése® (PIP), pues la frecuencia de rotura y de aparición de siliconomas ha sido mayor que con prótesis de otras fábricas (9) .…”

Section: Introductionunclassified

“…Actualmente, el caso de las prótesis PIP continúa siendo un escándalo médico con impacto socioeconómico a nivel mundial, el cual ha afectado más de 300.000 mujeres en 65 países diferentes, incluyendo el nuestro (10) . Los siliconomas pueden ser asintomáticos o manifestarse como nódulos subcutáneos, masas, deformidades, cicatrices, úlceras o fístulas, o producir dolor crónico (7,11,12) . Las partículas de silicona pueden migrar por los tejidos blandos, los vasos linfáticos o los vasos sanguíneos a sitios distantes, y causar inflamación y formación de granulomas que, en algunos casos com-Figura 1.…”

Section: Introductionunclassified

Siliconoma por implantes mamarios PIP (PolyImplant Prothèse)

Galvis¹,

Rolon²

2017

rev. asoc. colomb. dermatol. cir. dematol.

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Los siliconomas, o granulomas por silicona, representan una reacción inflamatoria crónica y natural del huésped para frenar una sustancia extraña, en este caso, la silicona. Corresponden a una de las posibles complicaciones después de la rotura o fuga de gel de silicona desde implantes mamarios. Es de creciente importancia después de la problemática desencadenada con los implantes mamarios Poli Implant Prothése® (PIP), ya que la frecuencia de rotura es mayor que con las prótesis de otras fábricas, y llegaron a afectar más de 300.000 mujeres en 65 países diferentes. Se presenta el caso de una mujer de 50 años con historia de mamoplastia de aumento con implantes de gel de silicona de marca PIP, que cursó con ptosis mamaria, lipodistrofias localizadas y una masa axilar. Los hallazgos histopatológicos junto con la información clínica permitieron hacer un diagnóstico de siliconoma, resultado de la migración de silicona a partir de un implante de marca PIP con rotura extracapsular.

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Cutaneous Silicone Granuloma Mimicking Breast Cancer after Ruptured Breast Implant

Cited by 5 publications

References 14 publications

Giant siliconoma mimicking locally advanced breast cancer: A case report and review of literature

Giant siliconoma mimicking locally advanced breast cancer: A case report and review of literature

The Value of Ultrasound in the Evaluation of the Integrity of Silicone Breast Implants

Siliconoma por implantes mamarios PIP (PolyImplant Prothèse)

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