Cutaneous sequelae in neonatal lupus: A retrospective cohort study

Levy, Rebecca; Briggs, Lauren; Silverman, Earl D.; Pope, Elena; Lara‐Corrales, Irene

doi:10.1016/j.jaad.2019.09.083

Cited by 20 publications

(26 citation statements)

References 13 publications

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“…In particular, a subset of patients may present initially with multiple telangiectasias 5 . The rash may also appear in non‐sun exposed areas or be present at birth 7 . The majority of these lesions resolve after 6 months as maternal antibodies wane, but a minority may subsequently develop residual dyspigmentation, atrophic scars, or persistent telangiectasias 5,8 .…”

Section: Discussionmentioning

confidence: 99%

Palmar telangiectasias in a 4‐year‐old girl

Mark

Luu

Zlotoff

2022

Pediatric Dermatology

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Section: Discussionmentioning

confidence: 99%

Palmar telangiectasias in a 4‐year‐old girl

Mark

Luu

Zlotoff

2022

Pediatric Dermatology

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“…Avoidance of sun exposure is the mainstay of management for cutaneous manifestations. The management of NLE is primarily expectant, but complete resolution of the skin lesions takes within six to nine months [5,6,10]. Topical steroids have been used to expedite the resolution of the lesions.…”

Section: Discussionmentioning

confidence: 99%

A Neonate With Annular Cutaneous Lesions

Vega

Duque

Don-Pedro

et al. 2020

Cureus

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Neonatal lupus erythematosus is a rare disorder with a wide spectrum of clinical presentations. The disease can affect several systems, including the skin, heart, liver, and bone marrow. Thus, a recognition of its different presentations is vital for making a diagnosis. We describe the case of a neonate diagnosed with neonatal lupus, presenting with an acute onset of erythematous skin lesions as the sole manifestation. The patient's mother was healthy with no known medical history or relevant family history

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“…This syndrome can include permanent cardiac conduction defects (congenital heart block) and/or photosensitive skin rashes. In support of a role for the autoantibodies, the rash resolves when maternal antibodies are no longer detected in the child's circulation, although residual sequelae such as telangiectasia and scarring persist in a minority of patients [89]. In addition, cardiac tissues from affected neonates and fetuses show IgG deposition [18].…”

Section: Rnp-specific Autoantibodies In the Pathogenesis Of Aidsmentioning

confidence: 99%