Cutaneous sarcoidosis concurrently involved in the sclerotic fingers of a patient with systemic sclerosis

Clinical characteristics of sarcoidosis patients with systemic sclerosis‐specific autoantibody: Possible involvement of thymus and activation‐regulated chemokine and a review of the published works

“…While rare, the coexistence of sarcoidosis with SSc has been reported in the published work, and we found nine cases of cutaneous lesion of sarcoidosis described in detail (Table ). Together with our two cases (cases 1 and 3), a review of these cases revealed a predominance of females (100%), with a median age of 53 years . ACA was detected in six patients (6/11; 55%) and anti‐topoisomerase I antibody was observed in three.…”

“…Subcutaneous nodule or erythema nodosum were observed in one case each. We found that three out of 11 cases showed cutaneous sarcoidosis lesion on dorsa of the hands . All of these three cases showed non‐caseating epithelioid cell granulomas in the dermis with the thickened collagen bundles.…”

“…hands. 29,33,34 All of these three cases showed non-caseating epithelioid cell granulomas in the dermis with the thickened collagen bundles. In our present case 3, we also found noncaseating epithelioid cell granulomas with the thickened collagen bundles (Fig.…”

“…In other reports, we could not confirm the coexistence of sarcoid lesion and sclerotic change. Kato et al . suggested the possibility that peripheral vasculopathy caused by sarcoidal granuloma might have triggered the induction of scleroderma in their case.…”

“…Together with our two cases (cases 1 and 3), a review of these cases revealed a predominance of females (100%), with a median age of 53 years. 2,11,13,15,[28][29][30][31][32][33][34] ACA was detected in six patients (6/11; 55%) and anti-topoisomerase I antibody was observed in three. Only one patient had anti-RNA polymerase III antibody.…”