Cutaneous Reactions to Traditional Chemotherapy and Radiation Therapy

Kohn, Lucinda L.; Shah, Sonal D.

doi:10.1007/978-3-319-66200-8_7

Cited by 1 publication

(3 citation statements)

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“…38 One common skin reaction to bleomycin is flagellate erythema, which has been reported in both adults and children. 37, [39][40][41] This presents with pruritus and an erythematous or hyperpigmented linear eruption on the trunk and limbs, appearing within a few hours or up to 6 months after administration ( Figure 6). Dermal sclerosis can also result from bleomycin in adults and children, sometimes appearing within the lesions of flagellate erythema.…”

Section: Antitumor Antib I Oti C Smentioning

confidence: 99%

“…48 These are similar to cutaneous reactions seen in adults, which additionally include alopecia and pruritus. 39 Importantly, in this immunosuppressed population, "rash" not otherwise specified has a broad differential, including viral eruptions and fungal infection. Workup for diagnosis would include skin biopsy for histopathology and culture, as well as nasopharyngeal swab and pathogen-specific viral blood PCR testing, as appropriate.…”

Section: Top Oisomer a S E Inhib Itor Smentioning

confidence: 99%

“…9 Vinca alkaloids are vesicants that can lead to local irritation, at times progressing to ulceration, with extravasation. 35,39…”

Section: Pl Ant Alk Aloids/mitoti C Inhib Itor Smentioning

confidence: 99%

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Cutaneous reactions to pediatric cancer treatment: Part I. Conventional chemotherapy

Sous

Armstrong

Huang

et al. 2020

Pediatric Dermatology

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Cutaneous side effects of childhood cancer therapies contribute to patient morbidity and can negatively affect quality of life. Traditional cancer therapies target rapidly dividing tissues; thus, many of their side effects inevitably involve the skin, nails, and mucosal surfaces. It is important for clinicians to recognize cutaneous reaction patterns and understand the underlying mechanisms of chemotherapeutic agents to detect and manage symptoms early and allow for continuation of therapy. In this scoping review, we discuss common cutaneous reactions to traditional classes of chemotherapeutic agents and antineoplastic antibodies in children, with specific examples from each drug class.

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Section: Antitumor Antib I Oti C Smentioning

confidence: 99%

Section: Top Oisomer a S E Inhib Itor Smentioning

confidence: 99%