Cutaneous nephrology

Knable, Alfred L.

doi:10.1016/s0733-8635(02)00012-8

Cited by 11 publications

(8 citation statements)

References 47 publications

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“…Other factors speculated in the pathogenesis of xerosis such as caloric and protein malnutrition are more prevalent in the Indian scenario as compared to the west 5. In addition, the tropical climate with greater sun exposure and resultant chronic dehydration may be contributory 16. Poorer outcome in the form of dermatitis and lichenification was seen in patients with both xerosis and pruritus.…”

Section: Discussionmentioning

confidence: 99%

Comparison of cutaneous manifestations in chronic kidney disease with or without dialysis

Khanna

Singal

Kalra

2010

Postgraduate Medical Journal

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Section: Discussionmentioning

confidence: 99%

Comparison of cutaneous manifestations in chronic kidney disease with or without dialysis

Khanna

Singal

Kalra

2010

Postgraduate Medical Journal

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“…Kyrle's disease occurs in anywhere from 10% to 21% of ESRD patients undergoing hemodialysis. 61,62 The lesions in Kyrle's disease appear as 2-8 mm domeshaped papules with a keratotic plug distributed among the trunk buttocks and proximal extremities. Papules may coalesce into plaques often with a linear pattern and can be accompanied by intense pruritus.…”

Section: Acquired Perforating Disordermentioning

confidence: 99%

Dermatologic manifestations in end stage renal disease

Blaha

Nigwekar

Combs

et al. 2018

Hemodialysis International

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Skin manifestations are commonly seen in end stage renal disease (ESRD). Skin involvement in this population can be extensive and dramatically worsen quality of life. Close observation of the skin and nails of ESRD patients by clinicians allows for timely diagnosis and treatment, which ultimately improves quality of life and reduces mortality. In this article we focus on the cutaneous changes most commonly seen in ESRD patients. PubMed/Medline database search was done for published literature on skin manifestations in ESRD patients. All the available literature was reviewed and relevant articles were used to discuss about clinical features, pathogenesis, histology and treatment of each skin disorder in ESRD patients. Most commonly encountered skin manifestations in patients with ESRD are pruritus, xerosis, pigmentation changes, nail changes, perforating disorders, calcifying disorders, bullous dermatoses and nephrogenic systemic fibrosis. Skin manifestations in ESRD can be difficult to treat and multiple comorbidities in this patient population can exacerbate these disorders. Many of the treatment options are experimental with evidence largely derived from the case reports and small clinical trials. More large‐scale trials are needed to firmly establish evidence based treatment guidelines. Prompt evaluation and management of these disorders improve morbidity and quality of life in ESRD patients.

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“…8 They studied this in the cases of end stage renal disease or among patients undergoing dialysis. They stated that they could not trace the exact cause of such high occurrence of pruritus in their study.…”

Section: Discussionmentioning

confidence: 99%

“…Knable AL et al in their study stated that cases with hypocomplementemia and chronic cutaneous lupus erythematous can be taken as marker for silent nephritis. 8 Thus they should be evaluated by using renal function tests.…”

Section: Discussionmentioning

confidence: 99%

Clinical profile of patients with cutaneous disorders

Singh¹,

Dhruv²,

Thakur³

2017

Int J Res Med Sci

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Background: 50-75% of all the patients who are on dialysis suffer from significant xerosis. But the exact cause is difficult to trace. Acquired ichthyosis is seen in some patients. Atrophy of sebaceous glands is seen in patients with uraemia. Such patients also show overall decrease in sweet volume. Objective was to study the clinical profile of patients with cutaneous disorders.Methods: A hospital based prospective study was carried out from September 2012 to February 2013 at a tertiary care centre of Late Baliram Kashyap memorial government medical college, Jagdalpur, Chhattisgarh, India. A total of 50 patients with cutaneous disorders were studied with respect to their clinical profile. Patients not willing to participate in the present study as per the protocol were excluded from the study. But patients giving their willingness to participate in the present study as per the protocol of the study were included in the study.Results: The males constituted 58% of the total cases and the females constituted 42% of the total cases. Maximum patients were seen in the fourth and fifth decade of their life i.e. 24% followed by the age group of 31-40 years i.e. 22%. The most common cutaneous manifestation was pruritus in 24% of cases followed by xerosis in 16% of cases. Next most common cutaneous manifestation was Tinea versicolor inn 14% of cases followed by oral candidiasis in 8% of cases and scabies were seen in 6% of cases. Both among males and females, pruritus was the most common skin lesion seen.Conclusions: The most common cutaneous lesion found in the present study was pruritus in 24% of cases followed by xerosis (16%), Tinea versicolor (14%), oral candidiasis (8%) and scabies in 6% of cases. Cases of nail changes, herpes zoster, Tinea cruris, hyper pigmentation, folliculitis, Exfoliative dermatitis, and Kyrle’s disease, Vitiligo, Melisma and Keloid were also seems.

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Cutaneous nephrology

Abstract: There are numerous cutaneous findings that may be related to coexistent renal disease. An astute clinician may use careful skin examination to make early diagnosis of renal conditions in some cases, and institute appropriate therapy as soon as indicated.

Cited by 11 publications

References 47 publications

Comparison of cutaneous manifestations in chronic kidney disease with or without dialysis

Comparison of cutaneous manifestations in chronic kidney disease with or without dialysis

Dermatologic manifestations in end stage renal disease

Clinical profile of patients with cutaneous disorders

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