Cutaneous mucinoses

Weedon, David

doi:10.1016/b978-0-7020-3485-5.00014-0

Cited by 4 publications

(4 citation statements)

References 432 publications

(342 reference statements)

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“…7 It is postulated that the localized mucin pool results from increased hyaluronic acid production by fibroblasts in lieu of other connective tissue elements. 8 Follicular induction has been well described and reported overlying dermatofibromas. Additionally, it has been reported in association with a scar, hemangioma, dermatofibrosarcoma protuberans, basal cell carcinoma, Bowen's disease, and melanoma in situ.…”

Section: Discussionmentioning

confidence: 98%

Cutaneous Focal Mucinosis Causing Follicular Induction of the Epidermis

Tatsas

O'Leary²,

Wright³

et al. 2009

The American Journal of Dermatopathology

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Section: Discussionmentioning

confidence: 98%

Cutaneous Focal Mucinosis Causing Follicular Induction of the Epidermis

Tatsas

O'Leary²,

Wright³

et al. 2009

The American Journal of Dermatopathology

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“…In young lesions, the mucin collection is separated from the epidermis by stroma, but in older lesions, the mucin can show a subepidermal location and, in most cases, thinning of the epidermis . However, reviews of digital myxoid cysts and the relevant chapters in most dermatopathology books mention some other epidermal changes, such as hyperkeratosis, acanthosis, ulceration or atrophy …”

Section: Discussionmentioning

confidence: 99%

Transepidermal elimination of mucin is a very common but not yet reported phenomenon in digital myxoid cysts: a study of 35 cases

Fernández-Flores

2015

J Cutan Pathol

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We present a series of 35 cases of digital myxoid cyst in which we specifically looked for transepidermal migration of mucin. We found it in 57.14% of the cases (20/35). In these cases, there were collections of mucin in an intraepidermal bulla as well as multiple intercellular droplets of mucin in many cases. All cases of perforating mucinosis described so far in the literature have presented clinically as papular eruptions. We therefore conclude that (1) perforating mucinoses do not exclusively present as multiple papules but also occur as single lesions; (2) transepidermal elimination of mucin is a very common but not yet reported phenomenon in digital myxoid cysts; (3) the morphological findings suggest real transepidermal migration of the mucin instead of exposure of the mucin to the surface via ulceration.

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“…2 The histological findings of scleromyxoedema and scleroedema differ; the fibroblast proliferation that is evident in histological specimens of scleromyxoedema is absent in scleroedema. 51…”

Section: Scleroedemamentioning

confidence: 99%

“…Scleroedema is typically associated with a history of an antecedent upper respiratory infection, diabetes mellitus or blood dyscrasia 2 . The histological findings of scleromyxoedema and scleroedema differ; the fibroblast proliferation that is evident in histological specimens of scleromyxoedema is absent in scleroedema 51 …”

Section: Scleromyxoedemamentioning

confidence: 99%

Consensus statement on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxoedema and scleroedema

Knobler,

Geroldinger‐Simić,

Kreuter

et al. 2024

Acad Dermatol Venereol

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The term ‘sclerosing diseases of the skin’ comprises specific dermatological entities, which have fibrotic changes of the skin in common. These diseases mostly manifest in different clinical subtypes according to cutaneous and extracutaneous involvement and can sometimes be difficult to distinguish from each other. The present consensus provides an update to the 2017 European Dermatology Forum Guidelines, focusing on characteristic clinical and histopathological features, diagnostic scores and the serum autoantibodies most useful for differential diagnosis. In addition, updated strategies for the first‐ and advanced‐line therapy of sclerosing skin diseases are addressed in detail. Part 2 of this consensus provides clinicians with an overview of the diagnosis and treatment of scleromyxoedema and scleroedema (of Buschke).

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Cutaneous mucinoses

Cited by 4 publications

References 432 publications

Cutaneous Focal Mucinosis Causing Follicular Induction of the Epidermis

Cutaneous Focal Mucinosis Causing Follicular Induction of the Epidermis

Transepidermal elimination of mucin is a very common but not yet reported phenomenon in digital myxoid cysts: a study of 35 cases

Consensus statement on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxoedema and scleroedema

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