Cutaneous metastatic breast cancer simulating angiosarcoma on the face and neck of a woman

Calomarde-Rees, Laura; Llombart-Cussac, Beatriz; Requena-Caballero, C.; Traves-Zapata, Victor; Bancalari-Simon, Bernado; Guillén-Barona, C.

doi:10.1111/ddg.13526

Cited by 6 publications

(14 citation statements)

References 4 publications

(4 reference statements)

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“…In most cases the metastases present as skin-colored nodules or papules, sometimes also as plaques or lymphangiosis carcinomatosa [5]. Other manifestations, such as a zosteriform-arranged and angiosarcoma-like lesions have been described [6,7]. Alopecia neoplastica is rare and occurs most frequently in the context of breast carcinomas, although other entities such as metastasized melanoma have also been reported [8].…”

Section: Diagnosismentioning

confidence: 99%

Multiple alopecic patches in the hairy scalp area of a 28‐year‐old female patient

Keller

Pixberg

Hassel

2021

J Deutsche Derma Gesell

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Section: Diagnosismentioning

confidence: 99%

Multiple alopecic patches in the hairy scalp area of a 28‐year‐old female patient

Keller

Pixberg

Hassel

2021

J Deutsche Derma Gesell

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“…Angiosarcomas are aggressive malignant neoplasms of endothelial origin and have a poor prognosis. However, the diagnosis is frequently delayed due to its various presentations, which mimic other diseases such as cellulitis, rosacea and metastatic cancer [4]. One of the presentations, which DOI: 10.1111/ddg.14352…”

Section: Dear Editorsmentioning

confidence: 99%

Angiosarcoma presenting as a diffuse facial edematous induration: a rare and atypical clinical feature

Wada

Namiki

Takahashi

et al. 2021

J Deutsche Derma Gesell

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“…It is also a common neoplasm associated with cutaneous metastases. The morphology of the skin lesions secondary to metastatic breast cancer is variable in appearance [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

Pleomorphic Appearance of Breast Cancer Cutaneous Metastases

Cohen¹

2021

Cureus

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Cutaneous metastases occur in approximately 10% of oncology patients as a feature of a persistent solid tumor or the harbinger of recurrent neoplastic disease. However, they can be the presenting manifestation of an unsuspected visceral malignancy in one percent of previously cancer-free individuals. Metastatic skin lesions from breast carcinoma are diverse in their appearance. The clinical presentation of cutaneous metastases in three women with breast cancer is described and both the morphology of skin metastases caused by breast carcinoma and the conditions that are mimicked by breast cancer cutaneous metastases are reviewed. Skin metastases from breast carcinoma commonly appear as firm, flesh-colored to red, smooth or ulcerated or crusted, nodules, papules, and plaques on the ipsilateral chest wall and breast. However, unique sites of breast cancer cutaneous metastases are the eyelids, inframammary folds, ipsilateral lymphedematous arm, scalp, subungual nail bed, and umbilicus; in addition, skin metastases can occur in mastectomy scars and radiation therapy ports. Carcinoma erysipelatoides, carcinoma telangiectoides, and carcinoma en cuirasse are classic patterns of skin metastases that can be observed in breast cancer patients; carcinoma hemorrhagiectoides is a recently observed skin metastases pattern that has also been noted in oncology patients with breast carcinoma. The pleomorphic skin lesions of breast cancer metastases can masquerade as benign cutaneous lesions and tumors (such as a collision tumor, cyst, dermatofibroma, and milia-en-plaque), cutaneous malignancies (such as melanoma and non-melanoma skin cancers), infections (such as cellulitis, folliculitis, herpes zoster, and paronychia), reactive erythema (such as erythema annulare centrifugum, and urticaria), skin conditions (such as alopecia areata, dermatitis, hidradenitis suppurativa, and scleroderma), and vascular lesions (such as angiokeratoma, angiosarcoma, lymphangioma circumscriptum, purpura, and pyogenic granuloma). In addition, breast carcinoma cutaneous metastases can not only mimic other miscellaneous conditions such as erosions and ulcers, Paget's disease, and papillomatosis cutis lymphostatica but also have unusual morphology such as targetoid lesions or a sharply demarcated red infiltration of the nasal tip similar to a clown's nose. The possibility of a breast cancer cutaneous metastasis should be considered in the evaluation of a patient with breast cancer--and although less likely, in a cancer-free individual--who develops a new and/or a treatment-unresponsive cutaneous lesion. A biopsy of the skin lesion is necessary to confirm the diagnosis of breast cancer cutaneous metastasis.

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Cutaneous metastatic breast cancer simulating angiosarcoma on the face and neck of a woman

Cited by 6 publications

References 4 publications

Multiple alopecic patches in the hairy scalp area of a 28‐year‐old female patient

Multiple alopecic patches in the hairy scalp area of a 28‐year‐old female patient

Angiosarcoma presenting as a diffuse facial edematous induration: a rare and atypical clinical feature

Pleomorphic Appearance of Breast Cancer Cutaneous Metastases

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