Cutaneous metastasis revealing a relapse of gastric linitis: Another case

Kairouani, Mouna; Perrin, J.; Dietemann-Barabinot, Anne; Diab, Rafiq; Ruck, Stephane

doi:10.1016/j.ijscr.2012.11.001

Cited by 10 publications

(13 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cutaneous metastasis might represent the initial manifestation of an underlying gastric cancer or, as in the present case, it can develop during the late course of the disease signaling progressive or advanced disease. In some cases, cutaneous metastasis may indicate relapse or recurrence of gastric cancer 2 . In a recent review of 11 cases of cutaneous metastasis from SRC gastric carcinoma, cutaneous metastases preceded the diagnosis of gastric carcinoma in 64% of the cases 8…”

Section: Discussionmentioning

confidence: 99%

“…Hematogenous or lymphatic dissemination probably accounts for gastric cancer settling within the skin 2,5,8 . Direct extension of the tumor and iatrogenic surgical implantation might also be responsible for cutaneous metastases 4,9 …”

Section: Discussionmentioning

confidence: 99%

“…Overall survival following diagnosis of skin metastasis in gastric cancer is less than 1 year, with an average of 11.4 weeks (range: 2‐34 weeks) 4,8 . The treatment modalities in extensive or recurrent skin metastases of gastric cancer, along with visceral metastases, are palliative, consisting of chemotherapy, and radiotherapy, which are usually futile 2,4 …”

Section: Discussionmentioning

confidence: 99%

“…Cutaneous metastasis of gastric cancer is extremely rare; the prevalence ranges from 0.2% to 2.2% in different reports, with a male predominance 1‐3 . Gastric cancer, alone, is responsible for 5% to 7% of all cutaneous metastases; percentages reaching 20% have been reported from Japan 4,5 …”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Livedoid cutaneous metastasis of signet‐ring cell gastric carcinoma

et al. 2021

View full text Add to dashboard Cite

Cutaneous metastasis of gastric cancer is extremely rare. Nodular forms are more common and inflammatory forms are exceptionally encountered. Herein, we report a case of inflammatory cutaneous metastasis of signet‐ring cell gastric cancer (poorly cohesive gastric carcinoma with signet‐ring cell component) masquerading as livedo reticularis. To our knowledge, such a clinical presentation of cutaneous metastasis has not been reported for gastric cancer. It is imperative to preserve a high index of clinical suspicion for diagnosing cutaneous metastases. Our case highlights the importance of obtaining a skin biopsy in patients with a known history of internal malignancy. Bizarre, newly erupting, evolving, persistent, or treatment‐refractory dermatologic lesions (such as nodules, ulcers, erythematous, reticular, or livedoid patches) might be clues for an underlying internal malignancy and require prompt histopathological sampling. Personal medical history, histopathological examination, and immunohistochemical profiling are equally important in distinguishing primary cutaneous carcinomas from secondary metastatic deposits. Early recognition of a cutaneous metastasis might enable appropriate staging and timely intervention, thereby prolonging survival.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Livedoid cutaneous metastasis of signet‐ring cell gastric carcinoma

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Muscular metastasis from gastric cancer is a rare manifestation as well. Subcutaneous metastasis from gastric cancer is also rare, with a reported incidence of 0.8-1.0% [1][2][3]. Both muscular and subcutaneous metastases from gastric cancer are associated with a poor prognosis.…”

mentioning

confidence: 99%

Metachronous port site, muscular and subcutaneous metastases from a gastric adenocarcinoma: a case report and review of articles

et al. 2021

View full text Add to dashboard Cite

Background Port site metastasis (PSM) after curative gastrectomy for gastric cancer and muscular metastasis from gastric cancer are rare manifestations. Similarly, subcutaneous metastasis from gastric cancer is rare, and muscular and subcutaneous metastases are associated with poor prognosis. We report a case of long-term survival in a patient who underwent curative resection of gastric cancer and repeated recurrence of port site, muscular and subcutaneous metastases from gastric cancer, treated by resection. Case presentation A 75-year-old man was diagnosed with gastric cancer and referred to our department. Upper endoscopy demonstrated a 5-cm circumferential ulcerated lesion at the cardia. Biopsy findings showed a poorly differentiated tubular adenocarcinoma. He underwent laparoscopic total gastrectomy with lymph node dissection, and pathologic examination revealed a moderately differentiated tubular adenocarcinoma stage T4aN1M0 and IIIA according to the UICC (Union for International Cancer Control) classification. He refused adjuvant chemotherapy and was only carefully observed. Twenty-three months after the primary gastrectomy, computed tomography (CT) revealed an irregular mass near the port site wounds. Then the patient underwent mass resection, and the pathological diagnosis was consistent with metastatic adenocarcinoma, located in the subcutaneous tissue at the port site wounds. Thirteen months after the second surgery, CT revealed an enhanced mass in the abdominal wall. Positron emission tomography (PET) CT showed an elevated uptake in the rectus abdominis muscle and a standardized uptake value (SUV) of 3.1. The patient underwent another mass resection, and the pathological diagnosis was consistent with metastatic adenocarcinoma in the rectus abdominis muscle. Thirty-five months after the third surgery, CT revealed a mass in the left gluteal subcutaneous region. Furthermore, PET-CT revealed a 35-mm mass with an elevated SUV of 9.6. Another mass resection procedure was performed, and the pathological diagnosis was consistent with metastatic adenocarcinoma in the subcutaneous tissue. Since tumor cells were present at the resection margin, additional radiation therapy was performed. The patient has survived 78 months after primary gastrectomy. Conclusion The prognosis of muscular and subcutaneous metastases from gastric cancer is poor. However, if the metastatic tumor is solitary, surgical excision could be a feasible treatment option and might prolong survival.

show abstract