Cutaneous metastasis of prostate carcinoma treated with electron radiotherapy

Abstract

Introduction: Prostate carcinoma is typically diagnosed and treated, and it rarely manifests as cutaneous metastases. We herein report electron radiotherapy for the treatment of cutaneous metastases causing cellulitis, with a durable clinical response achieved. Case presentation: A 70-year-old male patient with scrotal cutaneous metastasis of prostate carcinoma was undergoing treatment with docetaxel chemotherapy due to recurring cellulitis originating from the scrotum, and his treatment was interrupted. We administered electron radiotherapy to the scrotal cutaneous metastasis lesions, as irradiation was difficult, and obtained a good clinical effect. Subsequently, he continued chemotherapy, and the scrotal lesions remained clear and dry with no recurring cellulitis for 1 year. Conclusion: Electron radiotherapy is one of the safe and effective treatment options for controlling cutaneous metastasis of prostate carcinoma. Keynote messageProstate carcinoma rarely manifests as cutaneous metastases. The patient complained of discomfort and a reduced quality of life, and the metastasis caused cellulitis, and treatment interruption. We obtained a good clinical effect by treating the spherical cutaneous metastasis lesions in the scrotum, where irradiation was difficult, using electron radiotherapy.

The efficacy of radiation therapy using the Quad Shot regimen in cutaneous metastasis from parotid gland cancer: A case report

“…Arase et al reported a case of cutaneous metastasis to the chest wall from prostate adenocarcinoma. In the case, durable tumor shrinkage and symptom relief were achieved after radiation therapy using 18 Gy in 3 fractions using electron 9 . Oike et al reported a case of cutaneous metastasis of non‐small cell lung cancer to the arm.…”

“…In the case, durable tumor shrinkage and symptom relief were achieved after radiation therapy using 18 Gy in 3 fractions using electron. 9 Oike et al reported a case of cutaneous metastasis of non‐small cell lung cancer to the arm. In that case, photon radiation therapy at 45 Gy in 15 fractions led to complete tumor remission and improved the patient's quality of life.…”

The efficacy of radiation therapy using the Quad Shot regimen in cutaneous metastasis from parotid gland cancer: A case report

“…In the case, durable tumor shrinkage and symptom relief was achieved after radiation therapy using 18 Gy in 3 fractions using electron. 9 Oike et al . reported a case of cutaneous metastasis of non-small cell lung cancer to the arm.…”

Cutaneous Metastasis of Prostate Adenocarcinoma: A Rare Presentation of a Common Disease

“…Electron radiation therapy has been employed as an effective palliative treatment for painful skin metastases. 21 , 22 Surgical excision and intralesional chemotherapy are also viable options for small and limited metastases. 9 , 10 Systemic chemotherapy has the advantage of potentially reducing the primary malignancy as well as visceral and osseous metastases.…”