Cutaneous metastases from breast cancer: Considerations for implementing rigorous evaluation of local therapies

Campana, Luca Giovanni; Gehl, Julie

doi:10.1002/jso.27057

Cited by 2 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These issues represent a matter of debate at MDT meetings, where the treatment decision-making still lacks essential information. Nevertheless, waiting for more robust evidence, the EP community is building consensus on some critical areas (e.g., procedural aspects, dosimetry, treatment planning) to lay the basis for future studies and integrate different approaches [ 197 , 212 , 254 , 267 ]. Then, the next step will be addressing specific clinical questions on individual tumour types.…”

Section: Discussionmentioning

confidence: 99%

“…The next step will be to assess whether these recommendations improved the quality of reporting of clinical ECT. To this aim, we endorse multi-institutional collaboration [ 149 ], high-quality clinical databases (e.g., the InspECT registry or the Registry on Percutaneous ElectroChemoTherapy [RESPECT, NCT05267080] on patients with liver tumours led by the Cardiovascular and Interventional Radiological Society of Europe), and comparative studies with other local therapies [ 211 , 212 ].…”

Section: Electrochemotherapymentioning

confidence: 99%

See 1 more Smart Citation

Pulsed Electric Fields in Oncology: A Snapshot of Current Clinical Practices and Research Directions from the 4th World Congress of Electroporation

Campana

Daud

Lancellotti

et al. 2023

Cancers

Self Cite

View full text Add to dashboard Cite

The 4th World Congress of Electroporation (Copenhagen, 9–13 October 2022) provided a unique opportunity to convene leading experts in pulsed electric fields (PEF). PEF-based therapies harness electric fields to produce therapeutically useful effects on cancers and represent a valuable option for a variety of patients. As such, irreversible electroporation (IRE), gene electrotransfer (GET), electrochemotherapy (ECT), calcium electroporation (Ca-EP), and tumour-treating fields (TTF) are on the rise. Still, their full therapeutic potential remains underappreciated, and the field faces fragmentation, as shown by parallel maturation and differences in the stages of development and regulatory approval worldwide. This narrative review provides a glimpse of PEF-based techniques, including key mechanisms, clinical indications, and advances in therapy; finally, it offers insights into current research directions. By highlighting a common ground, the authors aim to break silos, strengthen cross-functional collaboration, and pave the way to novel possibilities for intervention. Intriguingly, beyond their peculiar mechanism of action, PEF-based therapies share technical interconnections and multifaceted biological effects (e.g., vascular, immunological) worth exploiting in combinatorial strategies.

show abstract