Cutaneous Manifestations of Protein Allergy

In a previous paper 1 we discussed the dermal-respiratory aspect of allergy in a series of allergic infants and children. We are here concerned chiefly with an appraisal of the skin tests in these cases. The cases to be described consist of 114 infants and children all of whom had eczema when they were first seen. These include 42 infants (under 2 years) with eczema alone, 38 children with eczema alone, and 34 infants and children with eczema and a complicating respiratory allergy.Other publications in the literature have reported on skin test findings. We believe that our study is unique in the sense that each case was tested with at least 350 different proteins. Further, where it was difficult to interpret results, tests were repeated.For the most part the tests were performed by the scratch method. Early in the study the intradermal method was not employed in all cases. Subsequently, intradermal tests with inhalants and pollens were included in all. We learned that in¬ tradermal tests to inhalants and pollens in the young children are essential, because young children usually have a low grade of sensitivity to these substances and the scratch test does not reveal their presence as often as does the intradermal test.Scratch tests with foods, on the other hand, are quite satisfactory, intradermal tests giv¬ ing too many false-positive results.About 97% reacted to one or more skin tests, which are described in Table 1.

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Cutaneous Manifestations of Protein Allergy

Cited by 8 publications

References 24 publications

The Leukopenic Index Test in Atopic Dermatitis

The Leukopenic Index Test in Atopic Dermatitis

Progress in Otolaryngology: A Summary of the Bibliographic Material Available in the Field of Otolaryngology * ADVANCEMENT IN THE KNOWLEDGE OF ALLERGY AS RELATED TO OTOLARYNGOLOGY

Analysis of Protein Skin Reactivity in Infantile and Childhood Eczema

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