Cutaneous manifestations of early human immunodeficiency virus exposure

Berger, R.; Stoner, Mary F.; Hobbs, Edmund R.; Hayes, Thomas J.; Boswell, R N

doi:10.1016/s0190-9622(88)70175-9

Cited by 58 publications

(22 citation statements)

References 16 publications

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“…9 Further studies showed tha the prevalence of seborrheic dermatitis in patients with HIV differs according to various authors. [10][11][12] It appears that the subtype of Malassezia sp. and level of CD4 + T cell are found to be risk factors of seborrheic dermatitis in patients of HIV/AIDS.…”

Section: Abstrakmentioning

confidence: 99%

Low CD4+ T cell counts are not risk factor for Malassezia species infection in HIV/AIDS patients

Panjaitan¹,

Pudjiati

Siswati

2014

JMedScie

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Human immunodefiiency virus (HIV) infection and aquired immunodeficiency syndrome (AIDS)cause a progressive depletion of CD4 + T cell populations accompanied by progressive impairment of cellular immunity and increasing susceptibility to opportunistic infections. Seborrheic dermatitis is one of the most common skin opportunistic infections on HIV/AIDS patients. Malassezia species is bilieved as the causative of seborrheic dermatitis. The aim of the study was to evaluate low CD4 + T cell counts as risk factor for Malassezia sp. infection in HIV/AIDS patients. This was an observational study with cross-sectional design conducted on HIV/AIDS patients who attended in Department of Dermatology and Venereology, Faculty of Medicine Universitas Gadjah Mada/ Dr Sardjito General Hospital, Yogyakarta and met the inclusion and exclusion criteria. Culture of Malassezia sp. was conducted in Department of Microbiology and classified as high (>100 CFU/ tape) and low (<100 CFU/tape) density colonies. CD4 Sci, Volume 46,No. 4, CFU/tape. Tidak ada hubungan bermakna adalah kadar sel T CD4 + dengan jumlah koloni Malassezia sp dalam penelitian ini (p=0,607; 95%CI=0,(4)(5)19; RP=0,452). Dapat disimpulkan, kadar sel T CD4 + yang rendah bukan merupakan faktor terjadinya infeksi Malassezia sp. pada penderita HIV/AIDS.

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Section: Abstrakmentioning

confidence: 99%

Low CD4+ T cell counts are not risk factor for Malassezia species infection in HIV/AIDS patients

Panjaitan¹,

Pudjiati

Siswati

2014

JMedScie

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“…For Soeprono et al, 85% of individuals with AIDS have SD, whereas Berger reported this figure as 36%, Goodman as 32% and Blanes et al as 31% of patients. [92][93][94][95][96][97][98][99][100][101][102] Malassezia spp. is also involved in the development of the disease.…”

Section: Seborrheic Dermatitis and Hivmentioning

confidence: 99%

Dermatite seborreica

Sampaio

Mameri²,

Vargas

et al. 2011

An. Bras. Dermatol.

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Seborrheic dermatitis is a chronic relapsing erythematous scaly skin disease, the prevalence of which is around 1 to 3% of the general population in the United States. It has two incidence peaks, the first in the first three months of life and the second beginning at puberty and reaching its apex at 40 to 60 years of age. The prevalence of seborrheic dermatitis is higher in HIV-positive individuals and the condition tends to be more intense and refractory to treatment in these patients. Neurological disorders and other chronic diseases are also associated with the onset of seborrheic dermatitis. The currently accepted theory on the pathogenesis of this disease advocates that yeast of Malassezia spp., present on the skin surface of susceptible individuals, leads to a non-immunogenic irritation due to the production of unsaturated fatty acids deposited on the skin surface. This article provides a review of the literature on seborrheic dermatitis, focusing on immunogenetics, the clinical forms of the disease and its treatment. . Keywords: Dermatitis; Dermatitis, seborrheic; Eczema Resumo: A dermatite seborreica é uma doença eritêmato-escamativa de caráter crônico-recidivante que acomete entre 1 e 3% da população geral dos Estados Unidos. Possui dois picos de incidência -o primeiro, durante os três primeiros meses de vida, e o segundo, a partir da puberdade, atingindo seu ápice entre os 40 e 60 anos de idade. Os indivíduos HIV positivos têm maior prevalência da doença, que apresenta maior intensidade e tendência à refratariedade ao tratamento. Doenças neurológicas e outras doenças crônicas também estão associadas ao desenvolvimento da dermatite seborreica. Como mecanismo fisiopatogênico, reconhece-se que o fungo Malassezia sp., presente na pele de indivíduos suscetíveis, leve a uma irritação não-imunogênica a partir da produção de metabólitos à base de áci-dos graxos insaturados deixados na superfície cutânea. Este artigo faz uma revisão da literatura sobre dermatite seborreica, com ênfase nos aspectos imunogenéticos, formas clínicas e tratamento.

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“…The prevalence of seborrhoeic dermatitis in this group was 36% (10). The severity of seborrhoeic dermatitis appeared to correlate to the grade of the immune state of patients and the stage of AIDS.…”

Section: Discussionmentioning

confidence: 68%

Seborrhoeic Dermatitis: Treatment with Anti‐Mycotic Agents

Sei

Hamaguchi

Ninomiya

et al. 1994

The Journal of Dermatology

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In order to elucidate the effectiveness of anti-mycotics in treating seborrhoeic dermatitis, an attempt was made to isolate Malassezia from seborrhoeic lesions of patients of seborrhoeic dermatitis. The results revealed that, in male patients, 46/49 cases were positive for Malassezia furfur on the face and 30/48 cases were positive for M. furfur on the scalp. In female patients, 7/13 cases were positive for M. furfur on the face, and 6/17 cases were positive for M. furfur on the scalp. Anti-mycotic agents were excellent in 50% and good in 31% of the spore-positive cases, yielding an overall efficacy rate of 81%. In contrast, the treatment of the face with vehicle alone showed only one excellent result out of 8 cases. Although clinical improvement was rapid on the side treated with a topical corticosteroid in the half-side-test, numerous fungal elements remained. While the improvement with anti-mycotic agents was slower than that with the corticosteroid, clinical improvement became evident by the third week of administration and fungal elements disappeared.

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Cutaneous manifestations of early human immunodeficiency virus exposure

Cited by 58 publications

References 16 publications

Low CD4+ T cell counts are not risk factor for Malassezia species infection in HIV/AIDS patients

Low CD4+ T cell counts are not risk factor for Malassezia species infection in HIV/AIDS patients

Dermatite seborreica

Seborrhoeic Dermatitis: Treatment with Anti‐Mycotic Agents

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