Cutaneous manifestations of diabetes mellitus and the metabolic syndrome

Karadağ, Ayşe Serap; Özlü, Emin; Lavery, Michael Joseph

doi:10.1016/j.clindermatol.2017.09.015

Cited by 28 publications

(38 citation statements)

References 32 publications

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“…However, it is known that psoriasis as multisystemic inflammatory disease is related to an increased cardiometabolic risk and that DM is a major contributor to cardiovascular morbidity and mortality 33 . There were authors who supported a view that psoriasis had the strongest association with metabolic syndrome among all skin diseases 34 . Several studies have shown that psoriasis is associated with diabetes and its complications.…”

Section: Discussionmentioning

confidence: 99%

Association between skin manifestations and glycemic control in patients with diabetes mellitus type II

2021

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Background/Aim. Diabetes mellitus can be associated with numerous skin diseases. This study aimed to determine the pattern and incidence of skin manifestations in patients with diabetes mellitus type II and their link to glycemic control. Methods. Prospective cross-sectional study was conducted at the Skin and Venereal Diseases Clinic, University Clinical Centre of the Republic of Srpska in Banja Luka, Bosnia and Herzegovina from January 2016 to January 2018. Adult patients of both genders suffering from diabetes mellitus type II and cutaneous manifestations participated in the study. Glycemic control was assessed according to values of glycated hemoglobin (HbA1c) of 7%. Results. Mean age of 105 study participants (46% male and 54% female) was 68.4 ± 10 years while mean HbA1c was 8.3 ± 1.6%. Unsatisfactory glycemic control was found in 74.3% of patients with mean HbA1c at 8.9 ± 1.4% while satisfactory glycemic control was found in 25.7% of patients with mean HbA1c at 6.7 ± 0.2% (p < 0.001). Most frequent skin diseases were infections (43.9%). Bacterial infections were most common (26.7%) followed by fungal infections (24.8%), xerosis (17.1%), psoriasis (15.2%), fibroma molle (14.3%), diabetic ulcer (7.7%), prurigo (6.7%), stasis dermatitis (5.7%). Other skin manifestations were found at a lower rate. Major link was found between unsatisfactory glycemic control and skin infections (p = 0.009). Conclusion. Most common skin manifestations in patients with diabetes type II are infections. Skin infections occurred more often in patients with unsatisfactory glycemic control.

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Section: Discussionmentioning

confidence: 99%

Association between skin manifestations and glycemic control in patients with diabetes mellitus type II

2021

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“…Eliminating insulin resistance or obesity may be of benefit in the early phases of the disorder. (Karadag, Ozlu, & Lavery, ) Metformin use, in order to eliminate insulin resistance, was shown to provide clinical improvement in acanthosis nigricans lesions. (Gong, Goswami, Giacomini, Altman, & Klein, ) In conjunction with life style changes and the use of insulin sensitizers, topical retinoids and keratolytics may be beneficial.…”

Section: Diseases Strongly Associated With Metabolic Syndrome and Thementioning

confidence: 99%

Metabolic syndrome in dermatology: Treatment and Management for Dermatologists

Engın

Özkoca

Kutlubay

et al. 2019

Dermatologic Therapy

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Metabolic syndrome, a commonly observed pathology and a global health issue, is closely related to the skin and thus dermatologists. The skin contributes to the development of metabolic syndrome and it is an end organ for it. Metabolic dysfunction is related to many skin disorders, some of which with high association and some of which with lower association. The diseases of highest association will be discussed in this article. These diseases are acne vulgaris, acanthosis nigricans, hidradenitis suppurativa, and psoriasis vulgaris.

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“…However, there are many other skin lesions which can be found in patients with diabetes. 16 These skin lesions are sometimes the first indication of the presence of systemic disease. Diabetes-related skin findings are more common in patients with poor glycemic control.…”

Section: Skin Complicationsmentioning

confidence: 99%

Complications of diabetes: beyond the heart, kidneys, and eyes

2019

Heart Metab

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Diabetes is a leading global health problem. Clinicians and most patients are aware that diabetes can lead to complications in the heart, kidneys, and eyes. Given the high morbidity and mortality, much effort is made to screen for and treat these complications. Other organ systems can also be affected by diabetes. The pathogenesis and risk factors for developing these other complications does not always match those for heart, kidneys, and eyes. Additionally, treatment for these other complications is often limited or absent. Here we will review some of the major musculoskeletal, neuropathic, and skin complications linked to diabetes.

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Cutaneous manifestations of diabetes mellitus and the metabolic syndrome

Cited by 28 publications

References 32 publications

Association between skin manifestations and glycemic control in patients with diabetes mellitus type II

Association between skin manifestations and glycemic control in patients with diabetes mellitus type II

Metabolic syndrome in dermatology: Treatment and Management for Dermatologists

Complications of diabetes: beyond the heart, kidneys, and eyes

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